ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PALB2
Symbol Alias	FLJ21816, FANCN
Approved Name	partner and localizer of BRCA2
Name Alias	Fanconi anemia, complementation group N
Location	16p12.1
Position	chr16:23614483-23652678, -
External Links	HGNC: 26144 Entrez Gene: 79728 Ensembl: ENSG00000083093 UCSC: uc002dlx.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16p12.3-12.2	chr16:16800000-24200000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0043066	negative regulation of apoptotic process	Biological Process		77
GO:0036342	post-anal tail morphogenesis	Biological Process		3
GO:0009887	organ morphogenesis	Biological Process		19
GO:0007498	mesoderm development	Biological Process		9
GO:0001833	inner cell mass cell proliferation	Biological Process		3
GO:0001756	somitogenesis	Biological Process		7
GO:0000724	double-strand break repair via homologous recombination	Biological Process	IDA[19423707]	12
GO:0006281	DNA repair	Biological Process		62
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005515	protein binding	Molecular Function	IPI[19423707]	910
GO:0003677	DNA binding	Molecular Function		220

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PALB2 (count: 5)

Gene Symbol	Pathway Count	Pathway List
ATM	7	negative regulation of apoptotic process; somitogenesis; double-strand break repair via homologous recombination; DNA repair; nucleoplasm; protein binding; DNA binding;
RELA	5	negative regulation of apoptotic process; organ morphogenesis; nucleoplasm; protein binding; DNA binding;
XRCC5	5	negative regulation of apoptotic process; DNA repair; nucleoplasm; protein binding; DNA binding;
H2AFX	5	double-strand break repair via homologous recombination; DNA repair; nucleoplasm; protein binding; DNA binding;
MRE11A	5	double-strand break repair via homologous recombination; DNA repair; nucleoplasm; protein binding; DNA binding;

Genes shared at least 2 KEGG pathways with PALB2 (count: 0)

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Region: chr16:23614483..23652678 View in gBrowse