ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DUSP2
Symbol Alias	PAC-1
Approved Name	dual specificity phosphatase 2
Location	2q11
Position	chr2:96808905-96811179, -1
External Links	HGNC: 3068 Entrez Gene: 1844 Ensembl: ENSG00000158050 UCSC: uc002svk.4
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 3)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0051019	mitogen-activated protein kinase binding	molecular function	IEA	4
GO:0042981	regulation of apoptotic process	biological process	IBA	34
GO:0005515	protein binding	molecular function	IPI	1015
GO:0005654	nucleoplasm	cellular component	IBA	210
GO:0001706	endoderm formation	biological process	IBA	3
GO:0008330	protein tyrosine/threonine phosphatase activity	molecular function	TAS[8107850]	2
GO:0035335	peptidyl-tyrosine dephosphorylation	biological process	TAS[7681221]	11
GO:0004725	protein tyrosine phosphatase activity	molecular function	IEA	19
GO:0017017	MAP kinase tyrosine/serine/threonine phosphatase activity	molecular function	IBA	3
GO:0005634	nucleus	cellular component	TAS[8107850]	877
GO:0006470	protein dephosphorylation	biological process	IBA	19
GO:0000188	inactivation of MAPK activity	biological process	IBA	3

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04010	MAPK signaling pathway	68

Genes shared at least 5 GO terms with DUSP2 (count: 3)

Gene Symbol	Pathway Count	Pathway List
DUSP1	8	regulation of apoptotic process; protein binding; nucleoplasm; endoderm formation; protein tyrosine/threonine phosphatase activity; MAP kinase tyrosine/serine/threonine phosphatase activity; protein dephosphorylation; inactivation of MAPK activity;
PTPN14	5	protein binding; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; nucleus; protein dephosphorylation;
CDC14B	5	nucleoplasm; peptidyl-tyrosine dephosphorylation; protein tyrosine phosphatase activity; nucleus; protein dephosphorylation;

Genes shared at least 2 KEGG pathways with DUSP2 (count: 0)

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Region: chr2:96808905..96811179 View in gBrowse