ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0042981
Name regulation of apoptotic process
Type biological process
No. of Genes in ADHDgene  34
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 34)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
UNC5B unc-5 homolog B (C. elegans) 10q22.2 1(0/0/1) TAS
PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 11p11.2 1(0/0/1) TAS
DUSP1 dual specificity phosphatase 1 5q35.1 1(0/1/0) IBA
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0) IEA
CAMK1D calcium/calmodulin-dependent protein kinase ID 10p13 1(0/0/1) IEA

Genes from other sources Help (count: 29)

Approved Symbol Approved Name Source Evidence[PMID]
CARD16 caspase recruitment domain family, member 16 Mapped by significant region IEA
DUSP2 dual specificity phosphatase 2 Mapped by LD-proxy IBA
UBB ubiquitin B Mapped by significant region TAS
UBC ubiquitin C Mapped by CNV TAS
PSME1 proteasome (prosome, macropain) activator subunit 1 (PA28 alpha) Mapped by significant region TAS
NOS1AP nitric oxide synthase 1 (neuronal) adaptor protein Mapped by CNV NAS
CARD17 caspase recruitment domain family, member 17 Mapped by significant region IEA
CARD18 caspase recruitment domain family, member 18 Mapped by significant region IEA
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 Mapped by significant region TAS
BCAR1 breast cancer anti-estrogen resistance 1 Mapped by significant region TAS[11607844]
ACTN3 actinin, alpha 3 (gene/pseudogene) Mapped by significant region NAS[16807302]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IDA[9949178]
CD3G CD3g molecule, gamma (CD3-TCR complex) Mapped by significant region IMP[12407027]
MALT1 mucosa associated lymphoid tissue lymphoma translocation gene 1 Mapped by significant region IDA[12819136]
TRAF1 TNF receptor-associated factor 1 Mapped by significant region IDA[10692572]
PSMA8 proteasome (prosome, macropain) subunit, alpha type, 8 Mapped by significant region TAS
CASP5 caspase 5, apoptosis-related cysteine peptidase Mapped by significant region IEA
TGFBR1 transforming growth factor, beta receptor 1 Mapped by significant region IDA[18758450]
CD3E CD3e molecule, epsilon (CD3-TCR complex) Mapped by significant region NAS[12567487]
PSMB7 proteasome (prosome, macropain) subunit, beta type, 7 Mapped by significant region TAS
TRAF7 TNF receptor-associated factor 7, E3 ubiquitin protein ligase Mapped by significant region IMP[15001576]
KIAA1324 KIAA1324 Mapped by CNV IMP
PSMD5 proteasome (prosome, macropain) 26S subunit, non-ATPase, 5 Mapped by significant region TAS
SGK1 serum/glucocorticoid regulated kinase 1 Mapped by significant region TAS
CARD6 caspase recruitment domain family, member 6 Mapped by significant region IEA
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region IMP[16207722]
RTN4 reticulon 4 Mapped by CNV NAS[11126360]
PSME2 proteasome (prosome, macropain) activator subunit 2 (PA28 beta) Mapped by significant region TAS
PSMG2 proteasome (prosome, macropain) assembly chaperone 2 Mapped by CNV IEA