ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DHFRP1
Approved Name	dihydrofolate reductase pseudogene 1
Location	18q11.2
Position	chr18:23747826-23751321, -
External Links	HGNC: 2862 Entrez Gene: 573971
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 22)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 22)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0050999	regulation of nitric-oxide synthase activity	Biological Process		5
GO:0050661	NADP binding	Molecular Function		6
GO:0046655	folic acid metabolic process	Biological Process		4
GO:0046654	tetrahydrofolate biosynthetic process	Biological Process		2
GO:0046653	tetrahydrofolate metabolic process	Biological Process		1
GO:0046209	nitric oxide metabolic process	Biological Process		4
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0031427	response to methotrexate	Biological Process		3
GO:0009165	nucleotide biosynthetic process	Biological Process		2
GO:0008144	drug binding	Molecular Function	IDA[15039552]	19
GO:0006767	water-soluble vitamin metabolic process	Biological Process		13
GO:0006766	vitamin metabolic process	Biological Process		13
GO:0006730	one-carbon metabolic process	Biological Process		9
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	Biological Process		7
GO:0000278	mitotic cell cycle	Biological Process		63
GO:0003729	mRNA binding	Molecular Function		10
GO:0004146	dihydrofolate reductase activity	Molecular Function	NAS[6687716]	1
GO:0005575	cellular_component	Cellular Component		98
GO:0005654	nucleoplasm	Cellular Component		183
GO:0005829	cytosol	Cellular Component		447
GO:0006545	glycine biosynthetic process	Biological Process		1
GO:0000082	G1/S transition of mitotic cell cycle	Biological Process		26

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DHFRP1 (count: 11)

Gene Symbol	Pathway Count	Pathway List
RRM2	6	small molecule metabolic process; regulation of transcription involved in G1/S phase of mitotic cell cycle; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
MTHFR	5	folic acid metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process; cytosol;
SHMT1	5	folic acid metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process; cytosol;
MOCOS	5	small molecule metabolic process; water-soluble vitamin metabolic process; vitamin metabolic process; cellular_component; cytosol;
PSMB7	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
PSMC3	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
PSMD5	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
PSMD7	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
PSME1	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
PSME2	5	small molecule metabolic process; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;
CDT1	5	regulation of transcription involved in G1/S phase of mitotic cell cycle; mitotic cell cycle; nucleoplasm; cytosol; G1/S transition of mitotic cell cycle;

Genes shared at least 2 KEGG pathways with DHFRP1 (count: 0)

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Region: chr18:23747826..23751321 View in gBrowse