ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DHFRP1
Approved Name	dihydrofolate reductase pseudogene 1
Location	18q11.2
Position	chr18:23749724-23751313, -1
External Links	HGNC: 2862 Entrez Gene: 573971 Ensembl: ENSG00000188985
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 22)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 22)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005654	nucleoplasm	cellular component	TAS	210
GO:0046655	folic acid metabolic process	biological process	TAS	4
GO:0005829	cytosol	cellular component	TAS	485
GO:0006766	vitamin metabolic process	biological process	TAS	13
GO:0003729	mRNA binding	molecular function	IDA	11
GO:0000278	mitotic cell cycle	biological process	TAS	66
GO:0046654	tetrahydrofolate biosynthetic process	biological process	IEA	2
GO:0004146	dihydrofolate reductase activity	molecular function	IDA; NAS[6687716]	1
GO:0008144	drug binding	molecular function	IDA[15039552]	20
GO:0000083	regulation of transcription involved in G1/S phase of mitotic cell cycle	biological process	TAS	7
GO:0050661	NADP binding	molecular function	IEA	8
GO:0046653	tetrahydrofolate metabolic process	biological process	IDA	1
GO:0006545	glycine biosynthetic process	biological process	NAS	1
GO:0000082	G1/S transition of mitotic cell cycle	biological process	TAS	27
GO:0006730	one-carbon metabolic process	biological process	IEA	5
GO:0044281	small molecule metabolic process	biological process	TAS	270
GO:0050999	regulation of nitric-oxide synthase activity	biological process	TAS	5
GO:0046209	nitric oxide metabolic process	biological process	TAS	4
GO:0009165	nucleotide biosynthetic process	biological process	NAS	2
GO:0005575	cellular_component	cellular component	ND	118
GO:0006767	water-soluble vitamin metabolic process	biological process	TAS	13
GO:0031427	response to methotrexate	biological process	IEA	3

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DHFRP1 (count: 11)

Gene Symbol	Pathway Count	Pathway List
RRM2	6	nucleoplasm; cytosol; mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
PSMD7	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
PSMD5	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
CDT1	5	nucleoplasm; cytosol; mitotic cell cycle; regulation of transcription involved in G1/S phase of mitotic cell cycle; G1/S transition of mitotic cell cycle;
PSME1	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
PSMB7	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
PSMC3	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
PSME2	5	nucleoplasm; cytosol; mitotic cell cycle; G1/S transition of mitotic cell cycle; small molecule metabolic process;
SHMT1	5	folic acid metabolic process; cytosol; vitamin metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process;
MTHFR	5	folic acid metabolic process; cytosol; vitamin metabolic process; small molecule metabolic process; water-soluble vitamin metabolic process;
MOCOS	5	cytosol; vitamin metabolic process; small molecule metabolic process; cellular_component; water-soluble vitamin metabolic process;

Genes shared at least 2 KEGG pathways with DHFRP1 (count: 0)

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Region: chr18:23749724..23751313 View in gBrowse