ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs7105122 dbSNP Ensembl
Location	Chr11:47449544(Fwd)
Variant Alleles	C/T
Ancestral Allele	T
Functional Annotation	upstream_gene_variant.
Consequence to Transcript	upstream_gene_variant(ENST00000530651; ENST00000524447; ENST00000298852; ENST00000530887; ENST00000531051; ENST00000530912; ENST00000527906; ENST00000526993; ENST00000531653; ENST00000528362; ENST00000529500)
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Hinney, A., 2011		C	GWAS P-value=9.10E-06, OR=1.47, Replication FBAT P-value=0.5...... GWAS P-value=9.10E-06, OR=1.47, Replication FBAT P-value=0.5279, Combination P-value=1.76E-05 More...	This GWAS in a small group of clinically ascertained young G...... This GWAS in a small group of clinically ascertained young German patients with ADHD and population-based controls did not reveal genome-wide significant findings. Replication attempts in further German and international samples did also not lead to a P-value(s) below 5E-08. More...	Trend

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
PSMC3	proteasome (prosome, macropain) 26S subunit, ATPase, 3	11p11.2	1(0/0/1)

Genes from other sources (count: 0)

SNPs in LD with rs7105122 (count: 34) View in gBrowse (chr11:47396654..47633506 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 34)

rs_ID	Functional Annotation	r²[population]
rs4147730	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs17790804	intron_variant; nc_transcript_variant; non_coding_exon_variant	0.944[JPT]
rs2242511	downstream_gene_variant; intron_variant	0.934[JPT]
rs4752837	intron_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs7948705	5_prime_UTR_variant; upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs7126210	downstream_gene_variant; intron_variant; nc_transcript_variant; synonymous_variant	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs10742816	downstream_gene_variant; upstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs11824864	intron_variant; nc_transcript_variant; upstream_gene_variant	0.944[JPT]
rs3740684	intron_variant	1.0[CEU]; 1.0[CHB]; 0.976[CHD]; 1.0[GIH]; 0.945[JPT]; 0.947[MEX]; 1.0[TSI]
rs17198158		0.921[GIH]; 0.944[JPT]
rs3824867	intron_variant	1.0[CEU]; 1.0[CHB]; 0.926[CHD]; 0.961[GIH]; 1.0[JPT]; 0.897[MEX]; 0.854[TSI]
rs9666924	intron_variant; upstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs10742806	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs2138767		0.921[GIH]; 0.944[JPT]; 0.866[MKK]
rs4752783	intron_variant	0.921[GIH]; 0.944[JPT]
rs1474056	downstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs4752839	downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant	0.844[GIH]; 0.89[JPT]
rs4752786		0.921[GIH]; 0.944[JPT]; 0.866[MKK]
rs11828339	downstream_gene_variant; upstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs4282946	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs10742805	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs4237544		1.0[CEU]; 1.0[CHB]; 1.0[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]
rs11039237	downstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]
rs7105907	upstream_gene_variant	1.0[CEU]; 1.0[CHB]; 1.0[JPT]; 1.0[YRI]
rs753812	intron_variant; upstream_gene_variant	0.918[GIH]; 0.942[JPT]
rs12419342	intron_variant	1.0[CHB]; 1.0[JPT]
rs4752829	intron_variant	1.0[CEU]; 1.0[CHB]; 0.937[JPT]
rs7931089	downstream_gene_variant	0.924[JPT]
rs1044269	3_prime_UTR_variant; downstream_gene_variant	0.92[GIH]; 0.944[JPT]
rs4752843	downstream_gene_variant; intron_variant	0.921[GIH]; 0.944[JPT]
rs11819955	intron_variant; upstream_gene_variant	0.93[JPT]
rs11821917	intron_variant; nc_transcript_variant; upstream_gene_variant	0.944[JPT]
rs3847503	intron_variant; upstream_gene_variant	0.921[GIH]; 0.944[JPT]
rs7111873	synonymous_variant	1.0[CEU]; 1.0[CHB]; 0.952[CHD]; 1.0[GIH]; 1.0[JPT]; 1.0[MEX]; 1.0[TSI]