ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol STS
Previous Symbol ARSC1
Symbol Alias ARSC
Approved Name steroid sulfatase (microsomal), isozyme S
Previous Name "steroid sulfatase (microsomal), arylsulfatase C, isozyme S"
Name Alias "arylsulfatase C"
Location Xp22.32
Position chrX:7137497-7272851, 1
External Links HGNC: 11425
Entrez Gene: 412
Ensembl: ENSG00000101846
UCSC: uc004cry.4
No. of Studies 3 (significant: 2; non-significant: 1; trend: 0)
Source Literature-origin; Mapped by Literature SNP

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Stergiakouli E, 2011 They did not replicate the previously identified association with rs12861247 in this case-control sample Non-significant
Brookes KJ, 2010 7 SNPs had significant evidence for association, but cannot survive stringent correction for multiple testing; haplotype CGGTTCTGCTGG P-value=0.02, X2 =10.13, but did not survive Bonferroni correction Significant
Brookes KJ, 2008(b) STS global P-value=0.039; haplotype-specific P-value=0.03, OR=1.52; support the hypothesis that the STS gene is a potential candidate for ADHD susceptibility Significant

Gene related SNPs (count: 56)

Literature-origin SNPs (count: 14)

LD-proxies (count: 42)


Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 22)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 22)


Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with STS (count: 41)

Genes shared at least 2 KEGG pathways with STS (count: 0)

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Region: chrX:7137497..7272851 View in gBrowse
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