ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

GO Report

Basic Info

ID	GO:0005764
Name	lysosome
Type	cellular component
No. of Genes in ADHDgene	34
Source	Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 34)

Literature-origin genes (count: 5)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)	Evidence[PMID]
ADRB2	adrenoceptor beta 2, surface	5q31-q32	2(1/1/0)	TAS[9507004]
STS	steroid sulfatase (microsomal), isozyme S	Xp22.32	3(2/1/0)	TAS[2668275]
TSPAN8	tetraspanin 8	12q14.1-q21.1	1(0/1/0)	TAS[8661157]
ANK3	ankyrin 3, node of Ranvier (ankyrin G)	10q21	2(0/2/0)	IEA
ARSB	arylsulfatase B	5q14.1	1(0/0/1)	TAS[2303452]

Genes from other sources (count: 29)

Approved Symbol	Approved Name	Source	Evidence[PMID]
TYR	tyrosinase	Mapped by significant region	TAS[11092760]
PRCP	prolylcarboxypeptidase (angiotensinase C)	Mapped by significant region	IEA
CCDC115	coiled-coil domain containing 115	Mapped by significant region	IEA
RAB14	RAB14, member RAS oncogene family	Mapped by significant region; Mapped by PBA pathway	ISS
CTSC	cathepsin C	Mapped by significant region	TAS[7665576]
VPS33B	vacuolar protein sorting 33 homolog B (yeast)	Mapped by LD-proxy	IDA[15052268]
UVRAG	UV radiation resistance associated	Mapped by significant region	IDA[19270696]
SYT7	synaptotagmin VII	Mapped by significant region	IEA
SQSTM1	sequestosome 1	Mapped by CNV	IEA
UNC93B1	unc-93 homolog B1 (C. elegans)	Mapped by significant region	ISS
USE1	unconventional SNARE in the ER 1 homolog (S. cerevisiae)	Mapped by PBA pathway	ISS[16354670]
TLR9	toll-like receptor 9	Mapped by LD-proxy	ISS
CTSF	cathepsin F	Mapped by significant region	TAS[9822672]
RAB27A	RAB27A, member RAS oncogene family	Mapped by LD-proxy	IDA[15548590]
AP5S1	adaptor-related protein complex 5, sigma 1 subunit	Mapped by CNV	IDA
PON2	paraoxonase 2	Mapped by PBA pathway	IEA
GJA1	gap junction protein, alpha 1, 43kDa	Mapped by Literature SNP; Mapped by significant region	IEA
DOC2A	double C2-like domains, alpha	Mapped by CNV	IEA
SIAE	sialic acid acetylesterase	Mapped by significant region	IEA
SLC11A1	solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1	Mapped by significant region	ISS
TNFAIP3	tumor necrosis factor, alpha-induced protein 3	Mapped by significant region	IEA
ZNRF1	zinc and ring finger 1, E3 ubiquitin protein ligase	Mapped by significant region	IEA
PRDX6	peroxiredoxin 6	Mapped by significant region; Mapped by PBA pathway	IEA
LAMTOR1	late endosomal/lysosomal adaptor, MAPK and MTOR activator 1	Mapped by significant region	IDA
KIAA1324	KIAA1324	Mapped by CNV	IDA
RPTOR	regulatory associated protein of MTOR, complex 1	Mapped by LD-proxy	IDA
NPC1	Niemann-Pick disease, type C1	Mapped by significant region	ISS
TPP1	tripeptidyl peptidase I	Mapped by CNV	IDA[15317752]; IMP[9295267]
NAAA	N-acylethanolamine acid amidase	Mapped by CNV	IEA