ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005764
Name lysosome
Type cellular component
No. of Genes in ADHDgene  34
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 34)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
ADRB2 adrenoceptor beta 2, surface 5q31-q32 2(1/1/0) TAS[9507004]
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS[2668275]
TSPAN8 tetraspanin 8 12q14.1-q21.1 1(0/1/0) TAS[8661157]
ANK3 ankyrin 3, node of Ranvier (ankyrin G) 10q21 2(0/2/0) IEA
ARSB arylsulfatase B 5q14.1 1(0/0/1) TAS[2303452]

Genes from other sources Help (count: 29)

Approved Symbol Approved Name Source Evidence[PMID]
TYR tyrosinase Mapped by significant region TAS[11092760]
PRCP prolylcarboxypeptidase (angiotensinase C) Mapped by significant region IEA
CCDC115 coiled-coil domain containing 115 Mapped by significant region IEA
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway ISS
CTSC cathepsin C Mapped by significant region TAS[7665576]
VPS33B vacuolar protein sorting 33 homolog B (yeast) Mapped by LD-proxy IDA[15052268]
UVRAG UV radiation resistance associated Mapped by significant region IDA[19270696]
SYT7 synaptotagmin VII Mapped by significant region IEA
SQSTM1 sequestosome 1 Mapped by CNV IEA
UNC93B1 unc-93 homolog B1 (C. elegans) Mapped by significant region ISS
USE1 unconventional SNARE in the ER 1 homolog (S. cerevisiae) Mapped by PBA pathway ISS[16354670]
TLR9 toll-like receptor 9 Mapped by LD-proxy ISS
CTSF cathepsin F Mapped by significant region TAS[9822672]
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy IDA[15548590]
AP5S1 adaptor-related protein complex 5, sigma 1 subunit Mapped by CNV IDA
PON2 paraoxonase 2 Mapped by PBA pathway IEA
GJA1 gap junction protein, alpha 1, 43kDa Mapped by Literature SNP; Mapped by significant region IEA
DOC2A double C2-like domains, alpha Mapped by CNV IEA
SIAE sialic acid acetylesterase Mapped by significant region IEA
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 Mapped by significant region ISS
TNFAIP3 tumor necrosis factor, alpha-induced protein 3 Mapped by significant region IEA
ZNRF1 zinc and ring finger 1, E3 ubiquitin protein ligase Mapped by significant region IEA
PRDX6 peroxiredoxin 6 Mapped by significant region; Mapped by PBA pathway IEA
LAMTOR1 late endosomal/lysosomal adaptor, MAPK and MTOR activator 1 Mapped by significant region IDA
KIAA1324 KIAA1324 Mapped by CNV IDA
RPTOR regulatory associated protein of MTOR, complex 1 Mapped by LD-proxy IDA
NPC1 Niemann-Pick disease, type C1 Mapped by significant region ISS
TPP1 tripeptidyl peptidase I Mapped by CNV IDA[15317752]; IMP[9295267]
NAAA N-acylethanolamine acid amidase Mapped by CNV IEA