ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RAB14
Symbol Alias	FBP, RAB-14
Approved Name	RAB14, member RAS oncogene family
Name Alias	"F protein-binding protein 1", "bA165P4.3 (member RAS oncogene family)", "small GTP binding protein RAB14"
Location	9q32-q34.11
Position	chr9:123940415-123985292, -1
External Links	HGNC: 16524 Entrez Gene: 51552 Ensembl: ENSG00000119396 UCSC: uc004blc.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region; Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q33	chr9:117700000-130300000	2 (1/1/0)

Gene related GO terms (count: 31)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 31)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005764	lysosome	cellular component	ISS	34
GO:0005622	intracellular	cellular component	IDA	83
GO:0009790	embryo development	biological process	ISS	19
GO:0005829	cytosol	cellular component	ISS	485
GO:0030670	phagocytic vesicle membrane	cellular component	IEA	9
GO:0005769	early endosome	cellular component	ISS	27
GO:0045335	phagocytic vesicle	cellular component	IDA	5
GO:0005795	Golgi stack	cellular component	ISS	9
GO:0046907	intracellular transport	biological process	NAS[15004230]	6
GO:0019003	GDP binding	molecular function	IDA[16034420]	8
GO:0006184	GTP catabolic process	biological process	IDA[16034420]; NAS[15004230]	24
GO:0032880	regulation of protein localization	biological process	IDA	7
GO:0015031	protein transport	biological process	IEA	89
GO:0008543	fibroblast growth factor receptor signaling pathway	biological process	ISS	33
GO:0055037	recycling endosome	cellular component	IDA	5
GO:0005791	rough endoplasmic reticulum	cellular component	ISS	8
GO:0005770	late endosome	cellular component	ISS	15
GO:0048471	perinuclear region of cytoplasm	cellular component	ISS	99
GO:0000139	Golgi membrane	cellular component	IEA	106
GO:0032456	endocytic recycling	biological process	IDA	5
GO:0005515	protein binding	molecular function	IPI[16034420]	1015
GO:0016192	vesicle-mediated transport	biological process	NAS[15004230]	33
GO:0031901	early endosome membrane	cellular component	IEA	9
GO:0007264	small GTPase mediated signal transduction	biological process	NAS	65
GO:0003924	GTPase activity	molecular function	IDA[16034420]; NAS[15004230]	46
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network	cellular component	ISS	1
GO:0005886	plasma membrane	cellular component	ISS	839
GO:0030140	trans-Golgi network transport vesicle	cellular component	ISS	7
GO:0007269	neurotransmitter secretion	biological process	NAS	21
GO:0005525	GTP binding	molecular function	IDA[16034420]	64
GO:0006895	Golgi to endosome transport	biological process	ISS; TAS[15004230]	4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAB14 (count: 38)

Gene Symbol	Pathway Count	Pathway List
ARF6	10	early endosome; GTP catabolic process; protein transport; recycling endosome; protein binding; vesicle-mediated transport; small GTPase mediated signal transduction; GTPase activity; plasma membrane; GTP binding;
RAB38	8	phagocytic vesicle membrane; phagocytic vesicle; GTP catabolic process; protein transport; small GTPase mediated signal transduction; GTPase activity; plasma membrane; GTP binding;
RAB27A	7	lysosome; GDP binding; late endosome; protein binding; small GTPase mediated signal transduction; GTPase activity; GTP binding;
RAB6A	7	cytosol; GTP catabolic process; Golgi membrane; protein binding; small GTPase mediated signal transduction; GTPase activity; GTP binding;
RAB27B	7	Golgi stack; GDP binding; protein transport; small GTPase mediated signal transduction; GTPase activity; trans-Golgi network transport vesicle; GTP binding;
RAB2A	7	GDP binding; GTP catabolic process; protein transport; Golgi membrane; small GTPase mediated signal transduction; GTPase activity; GTP binding;
EHD1	7	perinuclear region of cytoplasm; endocytic recycling; protein binding; early endosome membrane; GTPase activity; plasma membrane; GTP binding;
VPS33B	6	lysosome; protein transport; late endosome; perinuclear region of cytoplasm; protein binding; vesicle-mediated transport;
RAB6C	6	intracellular; GTP catabolic process; protein transport; small GTPase mediated signal transduction; GTPase activity; GTP binding;
MAPK3	6	cytosol; early endosome; fibroblast growth factor receptor signaling pathway; late endosome; protein binding; small GTPase mediated signal transduction;
MAPK1	6	cytosol; early endosome; fibroblast growth factor receptor signaling pathway; late endosome; protein binding; small GTPase mediated signal transduction;
RHOD	6	cytosol; GTP catabolic process; small GTPase mediated signal transduction; GTPase activity; plasma membrane; GTP binding;
RHOT2	6	cytosol; protein binding; small GTPase mediated signal transduction; GTPase activity; plasma membrane; GTP binding;
RAB39A	6	phagocytic vesicle membrane; phagocytic vesicle; protein transport; small GTPase mediated signal transduction; plasma membrane; GTP binding;
RAB30	6	Golgi stack; GTP catabolic process; protein transport; small GTPase mediated signal transduction; GTPase activity; GTP binding;
ARL2	6	GDP binding; GTP catabolic process; protein binding; small GTPase mediated signal transduction; GTPase activity; GTP binding;
RAB40C	6	GDP binding; protein transport; perinuclear region of cytoplasm; small GTPase mediated signal transduction; plasma membrane; GTP binding;
EHD3	6	perinuclear region of cytoplasm; endocytic recycling; protein binding; GTPase activity; plasma membrane; GTP binding;
GJA1	5	lysosome; early endosome; Golgi membrane; protein binding; plasma membrane;
AP5S1	5	lysosome; cytosol; protein transport; late endosome; protein binding;
GSPT1	5	intracellular; GTP catabolic process; protein binding; GTPase activity; GTP binding;
HSPA8	5	intracellular; cytosol; protein binding; plasma membrane; neurotransmitter secretion;
GABARAPL2	5	intracellular; cytosol; protein transport; Golgi membrane; protein binding;
TSC2	5	cytosol; fibroblast growth factor receptor signaling pathway; perinuclear region of cytoplasm; protein binding; vesicle-mediated transport;
ARRB1	5	cytosol; protein transport; Golgi membrane; protein binding; plasma membrane;
RAN	5	cytosol; protein binding; small GTPase mediated signal transduction; GTPase activity; GTP binding;
SNCA	5	cytosol; rough endoplasmic reticulum; perinuclear region of cytoplasm; protein binding; plasma membrane;
ARHGAP32	5	cytosol; Golgi membrane; protein binding; small GTPase mediated signal transduction; plasma membrane;
ARHGAP5	5	cytosol; GTP catabolic process; small GTPase mediated signal transduction; GTPase activity; GTP binding;
SEC23A	5	cytosol; perinuclear region of cytoplasm; Golgi membrane; protein binding; vesicle-mediated transport;
GSK3B	5	cytosol; fibroblast growth factor receptor signaling pathway; perinuclear region of cytoplasm; protein binding; plasma membrane;
EIF2B1	5	cytosol; GDP binding; protein binding; plasma membrane; GTP binding;
GNAZ	5	cytosol; GTP catabolic process; GTPase activity; plasma membrane; GTP binding;
STX6	5	early endosome; perinuclear region of cytoplasm; Golgi membrane; protein binding; plasma membrane;
SORT1	5	early endosome; perinuclear region of cytoplasm; plasma membrane; trans-Golgi network transport vesicle; Golgi to endosome transport;
SEPT5	5	GTP catabolic process; protein binding; GTPase activity; plasma membrane; GTP binding;
GOPC	5	protein transport; Golgi membrane; protein binding; plasma membrane; trans-Golgi network transport vesicle;
RASD1	5	perinuclear region of cytoplasm; small GTPase mediated signal transduction; GTPase activity; plasma membrane; GTP binding;

Genes shared at least 2 KEGG pathways with RAB14 (count: 0)

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Region: chr9:123940415..123985292 View in gBrowse