ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	RAB14
Symbol Alias	FBP, RAB-14
Approved Name	RAB14, member RAS oncogene family
Name Alias	F protein-binding protein 1, "bA165P4.3 (member RAS oncogene family)", "small GTP binding protein RAB14"
Location	9q32-q34.11
Position	chr9:123940415-123985292, -
External Links	HGNC: 16524 Entrez Gene: 51552 Ensembl: ENSG00000119396 UCSC: uc004blc.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q33	chr9:117700000-130300000	2 (1/1/0)

Gene related GO terms (count: 32)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 31)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0045335	phagocytic vesicle	Cellular Component		4
GO:0042175	nuclear outer membrane-endoplasmic reticulum membrane network	Cellular Component		1
GO:0046907	intracellular transport	Biological Process	NAS[15004230]	6
GO:0031901	early endosome membrane	Cellular Component		9
GO:0030670	phagocytic vesicle membrane	Cellular Component		8
GO:0032880	regulation of protein localization	Biological Process		5
GO:0032456	endocytic recycling	Biological Process		4
GO:0055037	recycling endosome	Cellular Component		4
GO:0048471	perinuclear region of cytoplasm	Cellular Component		87
GO:0009790	embryo development	Biological Process		17
GO:0008543	fibroblast growth factor receptor signaling pathway	Biological Process		26
GO:0007269	neurotransmitter secretion	Biological Process		18
GO:0007264	small GTPase mediated signal transduction	Biological Process		58
GO:0030140	trans-Golgi network transport vesicle	Cellular Component		7
GO:0019003	GDP binding	Molecular Function	IDA[16034420]	6
GO:0016192	vesicle-mediated transport	Biological Process	NAS[15004230]	28
GO:0015031	protein transport	Biological Process		75
GO:0005795	Golgi stack	Cellular Component		9
GO:0005791	rough endoplasmic reticulum	Cellular Component		7
GO:0005770	late endosome	Cellular Component		14
GO:0005769	early endosome	Cellular Component		25
GO:0006895	Golgi to endosome transport	Biological Process	TAS[15004230]	4
GO:0006184	GTP catabolic process	Biological Process	IDA[16034420]; NAS[15004230]	22
GO:0005886	plasma membrane	Cellular Component		772
GO:0005829	cytosol	Cellular Component		447
GO:0000139	Golgi membrane	Cellular Component		95
GO:0003924	GTPase activity	Molecular Function	IDA[16034420]; NAS[15004230]	41
GO:0005622	intracellular	Cellular Component		67
GO:0005764	lysosome	Cellular Component		31
GO:0005515	protein binding	Molecular Function	IPI[16034420]	910
GO:0005525	GTP binding	Molecular Function	IDA[16034420]	53

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAB14 (count: 33)

Gene Symbol	Pathway Count	Pathway List
ARF6	10	recycling endosome; small GTPase mediated signal transduction; vesicle-mediated transport; protein transport; early endosome; GTP catabolic process; plasma membrane; GTPase activity; protein binding; GTP binding;
RAB38	8	phagocytic vesicle; phagocytic vesicle membrane; small GTPase mediated signal transduction; protein transport; GTP catabolic process; plasma membrane; GTPase activity; GTP binding;
RAB2A	8	Golgi vesicle transport; small GTPase mediated signal transduction; GDP binding; protein transport; GTP catabolic process; Golgi membrane; GTPase activity; GTP binding;
EHD1	7	early endosome membrane; endocytic recycling; perinuclear region of cytoplasm; plasma membrane; GTPase activity; protein binding; GTP binding;
RAB27A	7	small GTPase mediated signal transduction; GDP binding; late endosome; GTPase activity; lysosome; protein binding; GTP binding;
RAB27B	7	small GTPase mediated signal transduction; trans-Golgi network transport vesicle; GDP binding; protein transport; Golgi stack; GTPase activity; GTP binding;
RAB6A	7	small GTPase mediated signal transduction; GTP catabolic process; cytosol; Golgi membrane; GTPase activity; protein binding; GTP binding;
STX6	6	Golgi vesicle transport; perinuclear region of cytoplasm; early endosome; plasma membrane; Golgi membrane; protein binding;
EHD3	6	endocytic recycling; perinuclear region of cytoplasm; plasma membrane; GTPase activity; protein binding; GTP binding;
VPS33B	6	perinuclear region of cytoplasm; vesicle-mediated transport; protein transport; late endosome; lysosome; protein binding;
MAPK1	6	fibroblast growth factor receptor signaling pathway; small GTPase mediated signal transduction; late endosome; early endosome; cytosol; protein binding;
MAPK3	6	fibroblast growth factor receptor signaling pathway; small GTPase mediated signal transduction; late endosome; early endosome; cytosol; protein binding;
ARL2	6	small GTPase mediated signal transduction; GDP binding; GTP catabolic process; GTPase activity; protein binding; GTP binding;
RAB30	6	small GTPase mediated signal transduction; protein transport; Golgi stack; GTP catabolic process; GTPase activity; GTP binding;
RAB6C	6	small GTPase mediated signal transduction; protein transport; GTP catabolic process; GTPase activity; intracellular; GTP binding;
RHOD	6	small GTPase mediated signal transduction; GTP catabolic process; plasma membrane; cytosol; GTPase activity; GTP binding;
COPB1	5	Golgi vesicle transport; plasma membrane; cytosol; Golgi membrane; protein binding;
STEAP2	5	Golgi vesicle transport; trans-Golgi network transport vesicle; early endosome; plasma membrane; cytosol;
GSK3B	5	perinuclear region of cytoplasm; fibroblast growth factor receptor signaling pathway; plasma membrane; cytosol; protein binding;
RASD1	5	perinuclear region of cytoplasm; small GTPase mediated signal transduction; plasma membrane; GTPase activity; GTP binding;
SNCA	5	perinuclear region of cytoplasm; rough endoplasmic reticulum; plasma membrane; cytosol; protein binding;
SORT1	5	perinuclear region of cytoplasm; trans-Golgi network transport vesicle; early endosome; Golgi to endosome transport; plasma membrane;
HSPA8	5	neurotransmitter secretion; plasma membrane; cytosol; intracellular; protein binding;
ARHGAP32	5	small GTPase mediated signal transduction; plasma membrane; cytosol; Golgi membrane; protein binding;
ARHGAP5	5	small GTPase mediated signal transduction; GTP catabolic process; cytosol; GTPase activity; GTP binding;
RAN	5	small GTPase mediated signal transduction; cytosol; GTPase activity; protein binding; GTP binding;
GOPC	5	trans-Golgi network transport vesicle; protein transport; plasma membrane; Golgi membrane; protein binding;
EIF2B1	5	GDP binding; plasma membrane; cytosol; protein binding; GTP binding;
ARRB1	5	protein transport; plasma membrane; cytosol; Golgi membrane; protein binding;
GABARAPL2	5	protein transport; cytosol; Golgi membrane; intracellular; protein binding;
GJA1	5	early endosome; plasma membrane; Golgi membrane; lysosome; protein binding;
GNAZ	5	GTP catabolic process; plasma membrane; cytosol; GTPase activity; GTP binding;
SEPT5	5	GTP catabolic process; plasma membrane; GTPase activity; protein binding; GTP binding;

Genes shared at least 2 KEGG pathways with RAB14 (count: 0)

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Region: chr9:123940415..123985292 View in gBrowse