ADHDgene Database

Gene Report

Basic Info

Approved Symbol	RAB27B
Approved Name	RAB27B, member RAS oncogene family
Location	18q21.2
Position	chr18:52385091-52562747, 1
External Links	HGNC: 9767 Entrez Gene: 5874 Ensembl: ENSG00000041353 UCSC: uc002lfr.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by Literature SNP

Gene related studies (count: 0)

Gene related SNPs (count: 17)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs2311120	chr18:52477123(Fwd)	intron_variant	2(0/2/0)

rs_ID	Location	Functional Annotation
rs1833283	chr18:52501562(Fwd)	intron_variant; nc_transcript_variant
rs4800976	chr18:52502796(Fwd)	intron_variant; nc_transcript_variant
rs4800977	chr18:52502887(Fwd)	intron_variant; nc_transcript_variant
rs1819887	chr18:52503313(Fwd)	intron_variant; nc_transcript_variant
rs2008739	chr18:52483302(Fwd)	intron_variant
rs2016584	chr18:52485773(Fwd)	intron_variant
rs9945547	chr18:52491629(Fwd)	intron_variant; upstream_gene_variant
rs2018485	chr18:52465668(Fwd)	intron_variant
rs9945718	chr18:52491791(Fwd)	intron_variant; upstream_gene_variant
rs12604321	chr18:52502759(Fwd)	intron_variant; nc_transcript_variant
rs1972593	chr18:52505867(Fwd)	intron_variant; nc_transcript_variant
rs1833284	chr18:52503589(Fwd)	intron_variant; nc_transcript_variant
rs2006776	chr18:52504498(Fwd)	intron_variant; nc_transcript_variant
rs1819888	chr18:52507270(Fwd)	intron_variant; nc_transcript_variant
rs1978355	chr18:52515885(Fwd)	intron_variant; nc_transcript_variant
rs2008315	chr18:52484889(Fwd)	intron_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042589	zymogen granule membrane	cellular component	IEA	4
GO:0007264	small GTPase mediated signal transduction	biological process	IEA	65
GO:0005795	Golgi stack	cellular component	IDA[19966785]	9
GO:0016324	apical plasma membrane	cellular component	IEA	52
GO:0005525	GTP binding	molecular function	ISS	64
GO:0045921	positive regulation of exocytosis	biological process	IMP[19966785]	5
GO:0032585	multivesicular body membrane	cellular component	IDA[19966785]	2
GO:0030140	trans-Golgi network transport vesicle	cellular component	IDA[19966785]	7
GO:0071985	multivesicular body sorting pathway	biological process	IMP[19966785]	3
GO:0015031	protein transport	biological process	IEA	89
GO:0019003	GDP binding	molecular function	IDA	8
GO:0019904	protein domain specific binding	molecular function	IPI[16880209]	43
GO:0003924	GTPase activity	molecular function	ISS	46

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with RAB27B (count: 4)

Gene Symbol	Pathway Count	Pathway List
RAB27A	9	small GTPase mediated signal transduction; apical plasma membrane; GTP binding; positive regulation of exocytosis; multivesicular body membrane; multivesicular body sorting pathway; GDP binding; protein domain specific binding; GTPase activity;
RAB14	7	small GTPase mediated signal transduction; Golgi stack; GTP binding; trans-Golgi network transport vesicle; protein transport; GDP binding; GTPase activity;
RAB30	5	small GTPase mediated signal transduction; Golgi stack; GTP binding; protein transport; GTPase activity;
RAB2A	5	small GTPase mediated signal transduction; GTP binding; protein transport; GDP binding; GTPase activity;

Genes shared at least 2 KEGG pathways with RAB27B (count: 0)

View in gBrowse

Region: chr18:52385091..52562747 View in gBrowse