ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0003924
Name GTPase activity
Type molecular function
No. of Genes in ADHDgene  46
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 46)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1p13 1(1/0/0) IBA
DIRAS2 DIRAS family, GTP-binding RAS-like 2 9q22.32 1(1/0/0) IEA
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0) IBA
DNM1 dynamin 1 9q34 1(0/0/1) IEA
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) TAS[8243272]
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0) IBA

Genes from other sources Help (count: 40)

Approved Symbol Approved Name Source Evidence[PMID]
RNF112 ring finger protein 112 Mapped by significant region IEA
TUBA3D tubulin, alpha 3d Mapped by CNV; Mapped by significant region IEA
HBS1L HBS1-like (S. cerevisiae) Mapped by significant region IEA
RASL11B RAS-like, family 11, member B Mapped by CNV IEA
RAB2A RAB2A, member RAS oncogene family Mapped by PBA pathway IDA[16034420]
TUBA3E tubulin, alpha 3e Mapped by significant region IEA
EHD1 EH-domain containing 1 Mapped by significant region IEA
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway IEA
TUFM Tu translation elongation factor, mitochondrial Mapped by LD-proxy IEA
SRL sarcalumenin Mapped by significant region IEA
GSPT1 G1 to S phase transition 1 Mapped by significant region TAS[15326224]
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IDA[18243103]
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway TAS[1993656]
SRPR signal recognition particle receptor (docking protein) Mapped by significant region IEA
TUBA4A tubulin, alpha 4a Mapped by significant region IEA
RIT2 Ras-like without CAAX 2 Mapped by significant region NAS[8824319]
RHOT2 ras homolog family member T2 Mapped by significant region IEA
MTG1 mitochondrial ribosome-associated GTPase 1 Mapped by CNV IBA
DIRAS1 DIRAS family, GTP-binding RAS-like 1 Mapped by LD-proxy IEA
EHD3 EH-domain containing 3 Mapped by CNV IEA
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV TAS[11017080]
RAB30 RAB30, member RAS oncogene family Mapped by significant region TAS[9792283]
TUBG1 tubulin, gamma 1 Mapped by PBA pathway IEA
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy ISS
RASD1 RAS, dexamethasone-induced 1 Mapped by significant region IEA
RAN RAN, member RAS oncogene family Mapped by PBA pathway TAS[10400640]
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) Mapped by LD-proxy IBA
RHOD ras homolog family member D Mapped by significant region TAS[9116026]
RAB38 RAB38, member RAS oncogene family Mapped by significant region NAS[10910072]
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Mapped by LD-proxy IEA
ARL2 ADP-ribosylation factor-like 2 Mapped by significant region IMP[10831612]
ATL3 atlastin GTPase 3 Mapped by significant region NAS[18270207]
GNG10 guanine nucleotide binding protein (G protein), gamma 10 Mapped by significant region TAS[7665596]
TUBB3 tubulin, beta 3 class III Mapped by significant region IEA
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway IDA[16034420]; NAS[15004230]
GNG3 guanine nucleotide binding protein (G protein), gamma 3 Mapped by significant region TAS[10075696]
SEPT5 septin 5 Mapped by CNV TAS[9385360]
RAB6C RAB6C, member RAS oncogene family Mapped by significant region IDA[10455022]
RAB27B RAB27B, member RAS oncogene family Mapped by Literature SNP ISS
ARHGAP5 Rho GTPase activating protein 5 Mapped by significant region TAS[8537347]