ADHDgene Database

Gene Report

Basic Info

Approved Symbol	DNM1
Previous Symbol	DNM
Approved Name	dynamin 1
Location	9q34
Position	chr9:130965658-131017527, 1
External Links	HGNC: 2972 Entrez Gene: 1759 Ensembl: ENSG00000106976 UCSC: uc022bob.1
No. of Studies	1 (significant: 0; non-significant: 0; trend: 1)
Source	Literature-origin; Mapped by Literature SNP

Gene related studies (count: 1)

Reference	Statistical Values/Author Comments	Result of Statistical Analysis
Lesch KP, 2008	Trend associated SNP was mapped in this gene.	Trend

Gene related SNPs (count: 7)

rs_ID	Location	Functional Annotation	No. of Studies (significant/non-significant/trend)
rs2502731	chr9:130976557(Fwd)	intron_variant; upstream_gene_variant	1(0/0/1)

rs_ID	Location	Functional Annotation
rs2502728	chr9:130973058(Fwd)	intron_variant
rs3003602	chr9:130981064(Fwd)	intron_variant; nc_transcript_variant; upstream_gene_variant
rs16930313	chr9:130993397(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant
rs3003608	chr9:130984430(Fwd)	intron_variant; nc_transcript_variant; upstream_gene_variant
rs13285411	chr9:130997868(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant
rs9644916	chr9:130998850(Fwd)	intron_variant; nc_transcript_variant; NMD_transcript_variant; upstream_gene_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005525	GTP binding	molecular function	IEA	64
GO:0006184	GTP catabolic process	biological process	TAS[10944110]	24
GO:0006897	endocytosis	biological process	IMP[19706678]	26
GO:0032403	protein complex binding	molecular function	IEA	30
GO:0005515	protein binding	molecular function	IPI	1015
GO:0005543	phospholipid binding	molecular function	IEA	66
GO:0003924	GTPase activity	molecular function	IEA	46
GO:0030117	membrane coat	cellular component	IEA	1
GO:0031623	receptor internalization	biological process	IEA	10
GO:0008022	protein C-terminus binding	molecular function	IEA	42
GO:0006898	receptor-mediated endocytosis	biological process	IMP[10521508]	13
GO:0005874	microtubule	cellular component	IEA	62
GO:0042802	identical protein binding	molecular function	IPI	77
GO:0007032	endosome organization	biological process	IMP[19706678]	7

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DNM1 (count: 0)

Genes shared at least 2 KEGG pathways with DNM1 (count: 0)

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Region: chr9:130965658..131017527 View in gBrowse