ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0042802
Name identical protein binding
Type molecular function
No. of Genes in ADHDgene  77
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 77)

Literature-origin genes (count: 10)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SYP synaptophysin Xp11.23-p11.22 4(4/0/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) IEA
PRKD1 protein kinase D1 14q11 1(0/1/0) IPI[19135240]
ASMT acetylserotonin O-methyltransferase Xp22.3 and Yp11.3 1(1/0/0) IPI
PTPRG protein tyrosine phosphatase, receptor type, G 3p21-p14 1(0/0/1) IPI[19167335]
DNM1 dynamin 1 9q34 1(0/0/1) IPI
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IPI
BAIAP2 BAI1-associated protein 2 17q25 1(1/0/0) IPI[14752106]
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IPI[18614564]
ATXN1 ataxin 1 6p23 1(0/0/1) IPI[16713569]

Genes from other sources Help (count: 67)

Approved Symbol Approved Name Source Evidence[PMID]
SYT9 synaptotagmin IX Mapped by CNV IEA
PAK1 p21 protein (Cdc42/Rac)-activated kinase 1 Mapped by significant region IPI
RILPL2 Rab interacting lysosomal protein-like 2 Mapped by CNV IPI[16189514]
TRIM5 tripartite motif containing 5 Mapped by CNV IPI
TPD52L1 tumor protein D52-like 1 Mapped by significant region IPI[9484778]
PRKAB2 protein kinase, AMP-activated, beta 2 non-catalytic subunit Mapped by CNV IPI
CLDN5 claudin 5 Mapped by CNV ISS
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Mapped by significant region IPI[7527811]
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 Mapped by CNV IPI[16189514]
SQSTM1 sequestosome 1 Mapped by CNV IPI
ALAD aminolevulinate dehydratase Mapped by significant region IPI[11032836]
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Mapped by significant region IPI
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IPI[17997397]
CEP72 centrosomal protein 72kDa Mapped by significant region IEA
AMOTL1 angiomotin like 1 Mapped by significant region IDA[16019084]
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IDA[9437432]; IPI[10498867]
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) Mapped by PBA pathway IPI[16189514]
CPT1A carnitine palmitoyltransferase 1A (liver) Mapped by CNV; Mapped by significant region IEA
EED embryonic ectoderm development Mapped by significant region IPI[11124122]
KCTD13 potassium channel tetramerization domain containing 13 Mapped by CNV IEA
P2RX6 purinergic receptor P2X, ligand-gated ion channel, 6 Mapped by CNV IPI[15313628]
ALDOA aldolase A, fructose-bisphosphate Mapped by CNV TAS[14766013]
STAC3 SH3 and cysteine rich domain 3 Mapped by CNV IPI[16189514]
PON2 paraoxonase 2 Mapped by PBA pathway IDA[15772423]
ERBB2 v-erb-b2 avian erythroblastic leukemia viral oncogene homolog 2 Mapped by LD-proxy IPI
MAP1S microtubule-associated protein 1S Mapped by PBA pathway IEA
USP2 ubiquitin specific peptidase 2 Mapped by significant region IEA
MAP3K5 mitogen-activated protein kinase kinase kinase 5 Mapped by LD-proxy; Mapped by significant region IPI
CLDN9 claudin 9 Mapped by significant region ISS
C1QTNF3 C1q and tumor necrosis factor related protein 3 Mapped by significant region IEA
PYCRL pyrroline-5-carboxylate reductase-like Mapped by LD-proxy IEA
ALDOB aldolase B, fructose-bisphosphate Mapped by significant region IPI[10625657]
TRIP13 thyroid hormone receptor interactor 13 Mapped by significant region IEA
TNN tenascin N Mapped by significant region IEA
SKP2 S-phase kinase-associated protein 2, E3 ubiquitin protein ligase Mapped by significant region IPI
SSSCA1 Sjogren syndrome/scleroderma autoantigen 1 Mapped by significant region IEA
ACY3 aspartoacylase (aminocyclase) 3 Mapped by significant region IEA
C1QTNF2 C1q and tumor necrosis factor related protein 2 Mapped by significant region IEA
FADD Fas (TNFRSF6)-associated via death domain Mapped by significant region IPI[8681376]
TSSK2 testis-specific serine kinase 2 Mapped by CNV IPI[15044604]
MSANTD3 Myb/SANT-like DNA-binding domain containing 3 Mapped by significant region IEA
VIL1 villin 1 Mapped by significant region IPI[17606613]
SHMT2 serine hydroxymethyltransferase 2 (mitochondrial) Mapped by CNV IEA
RIPK3 receptor-interacting serine-threonine kinase 3 Mapped by significant region IPI
PRC1 protein regulator of cytokinesis 1 Mapped by PBA pathway IPI
RYR2 ryanodine receptor 2 (cardiac) Mapped by CNV; Mapped by PBA pathway IPI[10830164]
STK11 serine/threonine kinase 11 Mapped by CNV IPI
PTS 6-pyruvoyltetrahydropterin synthase Mapped by significant region IPI[16189514]
ATL3 atlastin GTPase 3 Mapped by significant region IDA[18270207]
KCNRG potassium channel regulator Mapped by LD-proxy IPI[19447967]
GPSM2 G-protein signaling modulator 2 Mapped by CNV IPI[15537540]
APOA1 apolipoprotein A-I Mapped by significant region IPI[8049247]
HOOK3 hook microtubule-tethering protein 3 Mapped by PBA pathway IPI[18799622]
MAP3K11 mitogen-activated protein kinase kinase kinase 11 Mapped by significant region IPI[9829970]
CTSC cathepsin C Mapped by significant region IEA
CBX3 chromobox homolog 3 Mapped by CNV; Mapped by significant region IPI
ZBTB16 zinc finger and BTB domain containing 16 Mapped by significant region IPI[9294197]
KMT2A lysine (K)-specific methyltransferase 2A Mapped by significant region IPI[11313484]
TPCN2 two pore segment channel 2 Mapped by CNV; Mapped by significant region IPI
TTK TTK protein kinase Mapped by PBA pathway IPI
GLUL glutamate-ammonia ligase Mapped by significant region IPI
CLDN6 claudin 6 Mapped by significant region ISS
AXIN1 axin 1 Mapped by significant region ISS
NDE1 nudE neurodevelopment protein 1 Mapped by CNV; Mapped by significant region IEA
PRPF19 pre-mRNA processing factor 19 Mapped by significant region IPI[16332694]
PLN phospholamban Mapped by significant region ISS
APLP2 amyloid beta (A4) precursor-like protein 2 Mapped by significant region IPI[16193067]