ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0006184
Name GTP catabolic process
Type biological process
No. of Genes in ADHDgene  24
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 24)

Literature-origin genes (count: 5)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DNM1 dynamin 1 9q34 1(0/0/1) TAS[10944110]
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0) IBA; TAS[2117645]
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0) IBA; TAS[1899283]
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1p13 1(1/0/0) IBA
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) TAS[8243272]

Genes from other sources Help (count: 19)

Approved Symbol Approved Name Source Evidence[PMID]
RAB30 RAB30, member RAS oncogene family Mapped by significant region TAS[9792283]
ARL2 ADP-ribosylation factor-like 2 Mapped by significant region IMP[10831612]
RHOD ras homolog family member D Mapped by significant region TAS[9116026]
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IDA[18243103]; TAS[2501306]
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway TAS[9233818]
GSPT1 G1 to S phase transition 1 Mapped by significant region TAS[15326224]
GNG10 guanine nucleotide binding protein (G protein), gamma 10 Mapped by significant region TAS[7665596]
RAB6C RAB6C, member RAS oncogene family Mapped by significant region IDA[10455022]
RAB2A RAB2A, member RAS oncogene family Mapped by PBA pathway IDA[16034420]; TAS[2501306]
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway TAS[1993656]
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV TAS[11017080]
ATL3 atlastin GTPase 3 Mapped by significant region NAS[18270207]
SEPT5 septin 5 Mapped by CNV TAS[9385360]
MTG1 mitochondrial ribosome-associated GTPase 1 Mapped by CNV IBA
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) Mapped by LD-proxy IBA
GNG3 guanine nucleotide binding protein (G protein), gamma 3 Mapped by significant region TAS[10075696]
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway IDA[16034420]; NAS[15004230]
ARHGAP5 Rho GTPase activating protein 5 Mapped by significant region TAS[8537347]
RAB38 RAB38, member RAS oncogene family Mapped by significant region NAS[10910072]