ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0032403
Name protein complex binding
Type molecular function
No. of Genes in ADHDgene  30
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 30)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SYP synaptophysin Xp11.23-p11.22 4(4/0/0) IEA
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 8q13.3 1(0/0/1) IEA
DNM1 dynamin 1 9q34 1(0/0/1) IEA
ARRB2 arrestin, beta 2 17p13 1(1/0/0) IEA
SLC6A3 solute carrier family 6 (neurotransmitter transporter), member 3 5p15.3 70(43/26/1) IEA
HTR2A 5-hydroxytryptamine (serotonin) receptor 2A, G protein-coupled 13q14-q21 13(7/6/0) IEA

Genes from other sources Help (count: 24)

Approved Symbol Approved Name Source Evidence[PMID]
RPTOR regulatory associated protein of MTOR, complex 1 Mapped by LD-proxy IPI[19211835]
STK11 serine/threonine kinase 11 Mapped by CNV IEA
KAT5 K(lysine) acetyltransferase 5 Mapped by significant region IEA
RNF40 ring finger protein 40, E3 ubiquitin protein ligase Mapped by CNV IEA
ERCC8 excision repair cross-complementing rodent repair deficiency, complementation group 8 Mapped by CNV IDA[16916636]
ATM ataxia telangiectasia mutated Mapped by CNV; Mapped by significant region IDA[15790808]
FLCN folliculin Mapped by significant region IDA[17028174]
UQCRC2 ubiquinol-cytochrome c reductase core protein II Mapped by CNV; Mapped by significant region IEA
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A Mapped by significant region IEA
CIITA class II, major histocompatibility complex, transactivator Mapped by significant region IDA[17493635]
PDCL phosducin-like Mapped by significant region IEA
CCND1 cyclin D1 Mapped by significant region IEA
PTCH1 patched 1 Mapped by significant region IEA
CTSV cathepsin V Mapped by significant region IEA
TELO2 telomere maintenance 2 Mapped by significant region IDA
UFD1L ubiquitin fusion degradation 1 like (yeast) Mapped by CNV IEA
PAFAH1B1 platelet-activating factor acetylhydrolase 1b, regulatory subunit 1 (45kDa) Mapped by PBA pathway IEA
SREBF1 sterol regulatory element binding transcription factor 1 Mapped by significant region IEA
CDK5RAP2 CDK5 regulatory subunit associated protein 2 Mapped by significant region IEA
FYB FYN binding protein Mapped by significant region IEA
CAV3 caveolin 3 Mapped by Literature SNP IDA[10988290]
TMED10 transmembrane emp24-like trafficking protein 10 (yeast) Mapped by PBA pathway IEA
STRN3 striatin, calmodulin binding protein 3 Mapped by significant region IDA[18782753]
SH2B3 SH2B adaptor protein 3 Mapped by LD-proxy IEA