ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005525
Name GTP binding
Type molecular function
No. of Genes in ADHDgene  64
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 64)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
DNAJC27 DnaJ (Hsp40) homolog, subfamily C, member 27 2p23.3 1(1/0/0) IEA
GNAZ guanine nucleotide binding protein (G protein), alpha z polypeptide 22q11.1-q11.2 1(0/1/0) IEA
DIRAS2 DIRAS family, GTP-binding RAS-like 2 9q22.32 1(1/0/0) IEA
GNAT2 guanine nucleotide binding protein (G protein), alpha transducing activity polypeptide 2 1p13 1(1/0/0) NAS[1936270]
GNAO1 guanine nucleotide binding protein (G protein), alpha activating activity polypeptide O 16q13 1(0/1/0) IEA
DNM1 dynamin 1 9q34 1(0/0/1) IEA
GNAL guanine nucleotide binding protein (G protein), alpha activating activity polypeptide, olfactory type 18p11.22-p11.21 1(1/0/0) IEA

Genes from other sources Help (count: 57)

Approved Symbol Approved Name Source Evidence[PMID]
SCG5 secretogranin V (7B2 protein) Mapped by CNV; Mapped by significant region TAS[3134253]
OPA1 optic atrophy 1 (autosomal dominant) Mapped by CNV IEA
TUBB3 tubulin, beta 3 class III Mapped by significant region IEA
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IDA[19141279]
ACSM5 acyl-CoA synthetase medium-chain family member 5 Mapped by significant region IEA
RAB27B RAB27B, member RAS oncogene family Mapped by Literature SNP ISS
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) Mapped by LD-proxy ISS
RAB26 RAB26, member RAS oncogene family Mapped by significant region IMP; ISS
RAN RAN, member RAS oncogene family Mapped by PBA pathway IDA[1961752]
RAB37 RAB37, member RAS oncogene family Mapped by CNV IEA
RAB1B RAB1B, member RAS oncogene family Mapped by significant region IDA
ARL17B ADP-ribosylation factor-like 17B Mapped by LD-proxy IEA
DRG2 developmentally regulated GTP binding protein 2 Mapped by significant region IEA
GUCY1A2 guanylate cyclase 1, soluble, alpha 2 Mapped by significant region IEA
RAB30 RAB30, member RAS oncogene family Mapped by significant region IEA
TUBA4A tubulin, alpha 4a Mapped by significant region IEA
SEPT12 septin 12 Mapped by significant region IDA[18443421]; ISS
ACSM1 acyl-CoA synthetase medium-chain family member 1 Mapped by significant region IEA
RNF112 ring finger protein 112 Mapped by significant region IEA
RHOT2 ras homolog family member T2 Mapped by significant region IEA
ARFIP2 ADP-ribosylation factor interacting protein 2 Mapped by CNV TAS[8670882]
SRL sarcalumenin Mapped by significant region IEA
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway TAS[10913182]
HBS1L HBS1-like (S. cerevisiae) Mapped by significant region IEA
RAB40C RAB40C, member RAS oncogene family Mapped by significant region IEA
RAB38 RAB38, member RAS oncogene family Mapped by significant region NAS[10910072]
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway IDA[16034420]
RASL11B RAS-like, family 11, member B Mapped by CNV IEA
RAB2A RAB2A, member RAS oncogene family Mapped by PBA pathway IDA[16034420]
RAB6C RAB6C, member RAS oncogene family Mapped by significant region IEA
THG1L tRNA-histidine guanylyltransferase 1-like (S. cerevisiae) Mapped by significant region IDA
TUBA3D tubulin, alpha 3d Mapped by CNV; Mapped by significant region NAS
TUBA4B tubulin, alpha 4b (pseudogene) Mapped by significant region IEA
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Mapped by LD-proxy IEA
SEPT5 septin 5 Mapped by CNV IEA
ARL2 ADP-ribosylation factor-like 2 Mapped by significant region IMP[10831612]
RIT2 Ras-like without CAAX 2 Mapped by significant region IEA
ATL3 atlastin GTPase 3 Mapped by significant region IEA
RAB39A RAB39A, member RAS oncogene family Mapped by significant region NAS[9119394]
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa Mapped by CNV IEA
EHD3 EH-domain containing 3 Mapped by CNV IEA
TUBA3E tubulin, alpha 3e Mapped by significant region IEA
GMPPA GDP-mannose pyrophosphorylase A Mapped by significant region IEA
GVINP1 GTPase, very large interferon inducible pseudogene 1 Mapped by CNV IEA
EFTUD2 elongation factor Tu GTP binding domain containing 2 Mapped by PBA pathway IEA
RASD1 RAS, dexamethasone-induced 1 Mapped by significant region IEA
GSPT1 G1 to S phase transition 1 Mapped by significant region IEA
TUFM Tu translation elongation factor, mitochondrial Mapped by LD-proxy IEA
SRPR signal recognition particle receptor (docking protein) Mapped by significant region IEA
DIRAS1 DIRAS family, GTP-binding RAS-like 1 Mapped by LD-proxy IEA
ARHGAP5 Rho GTPase activating protein 5 Mapped by significant region IEA
RAB27A RAB27A, member RAS oncogene family Mapped by LD-proxy ISS
EHD1 EH-domain containing 1 Mapped by significant region IEA
TUBG1 tubulin, gamma 1 Mapped by PBA pathway IEA
RHOD ras homolog family member D Mapped by significant region IEA
MTG1 mitochondrial ribosome-associated GTPase 1 Mapped by CNV IEA
SEPT1 septin 1 Mapped by CNV IEA