ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ARFIP2
Symbol Alias	POR1
Approved Name	ADP-ribosylation factor interacting protein 2
Name Alias	arfaptin 2
Location	11p15
Position	chr11:6496910-6502666, -
External Links	HGNC: 17160 Entrez Gene: 23647 Ensembl: ENSG00000132254 UCSC: uc001mdk.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_29	chr11:5582423-7488751 (NCBI Build 36.1 (hg18))	1859865	11p15.4	Loss	De novo

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 14)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048365	Rac GTPase binding	Molecular Function	TAS[9312003]	5
GO:0031529	ruffle organization	Biological Process	TAS[9312003]	5
GO:0030742	GTP-dependent protein binding	Molecular Function	IPI[9312003]; TAS[9312003]	2
GO:0030036	actin cytoskeleton organization	Biological Process	IMP[9312003]	21
GO:0030032	lamellipodium assembly	Biological Process	TAS[9312003]	8
GO:0001726	ruffle	Cellular Component	IMP[8670882]	14
GO:0007264	small GTPase mediated signal transduction	Biological Process	TAS[8670882]	58
GO:0019904	protein domain specific binding	Molecular Function		40
GO:0005938	cell cortex	Cellular Component	IDA[9312003]	26
GO:0006928	cellular component movement	Biological Process	TAS[8670882]	16
GO:0005737	cytoplasm	Cellular Component	TAS[9312003]	690
GO:0005886	plasma membrane	Cellular Component	TAS[9312003]	772
GO:0005515	protein binding	Molecular Function		910
GO:0005525	GTP binding	Molecular Function	TAS[8670882]	53

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ARFIP2 (count: 6)

Gene Symbol	Pathway Count	Pathway List
ARF6	8	ruffle organization; ruffle; small GTPase mediated signal transduction; cell cortex; cellular component movement; plasma membrane; protein binding; GTP binding;
CYFIP1	5	Rac GTPase binding; ruffle organization; lamellipodium assembly; ruffle; protein binding;
ADRA2A	5	actin cytoskeleton organization; cellular component movement; cytoplasm; plasma membrane; protein binding;
CORO1A	5	actin cytoskeleton organization; cellular component movement; cytoplasm; plasma membrane; protein binding;
NCK1	5	lamellipodium assembly; protein domain specific binding; cytoplasm; plasma membrane; protein binding;
SNCA	5	protein domain specific binding; cell cortex; cytoplasm; plasma membrane; protein binding;

Genes shared at least 2 KEGG pathways with ARFIP2 (count: 0)

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Region: chr11:6496910..6502666 View in gBrowse