ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SEPT1
Previous Symbol	DIFF6
Symbol Alias	PNUTL3
Approved Name	septin 1
Location	16p11.1
Position	chr16:30389454-30394171, -
External Links	HGNC: 2879 Entrez Gene: 1731 Ensembl: ENSG00000180096 UCSC: uc002dxy.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 1)

ID	Location	Size	Band	Type	Inheritance
CNV_Williams[2010]_34	chr16:29342178-31155425 (NCBI Build 36.1 (hg18))	1813248	16p11.2	Loss	De novo

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

ID	Name	Type	No. of Genes in ADHDgene
GO:0007049	cell cycle	Biological Process	31
GO:0005815	microtubule organizing center	Cellular Component	19
GO:0051301	cell division	Biological Process	58
GO:0031105	septin complex	Cellular Component	2
GO:0005525	GTP binding	Molecular Function	53
GO:0005515	protein binding	Molecular Function	910

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa05100	Bacterial invasion of epithelial cells	19	Many pathogenic bacteria can invade phagocytic and non-phago...... Many pathogenic bacteria can invade phagocytic and non-phagocytic cells and colonize them intracellularly, then become disseminated to other cells. Invasive bacteria induce their own uptake by non-phagocytic host cells (e.g. epithelial cells) using two mechanisms referred to as zipper model and trigger model. Listeria, Staphylococcus, Streptococcus, and Yersinia are examples of bacteria that enter using the zipper model. These bacteria express proteins on their surfaces that interact with cellular receptors, initiating signalling cascades that result in close apposition of the cellular membrane around the entering bacteria. Shigella and Salmonella are the examples of bacteria entering cells using the trigger model. These bacteria use type III secretion systems to inject protein effectors that interact with the actin cytoskeleton. More...

Genes shared at least 5 GO terms with SEPT1 (count: 0)

Genes shared at least 2 KEGG pathways with SEPT1 (count: 0)

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Region: chr16:30389454..30394171 View in gBrowse