ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ARL2
Symbol Alias	ARFL2
Approved Name	ADP-ribosylation factor-like 2
Location	11q13
Position	chr11:64781585-64789656, +
External Links	HGNC: 693 Entrez Gene: 402 Ensembl: ENSG00000213465 UCSC: uc001och.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 20)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0010811	positive regulation of cell-substrate adhesion	Biological Process		6
GO:0016328	lateral plasma membrane	Cellular Component		8
GO:0007049	cell cycle	Biological Process		31
GO:0007264	small GTPase mediated signal transduction	Biological Process		58
GO:0006184	GTP catabolic process	Biological Process	IMP[10831612]	22
GO:0007021	tubulin complex assembly	Biological Process	TAS[10831612]	2
GO:0005758	mitochondrial intermembrane space	Cellular Component	IDA[11809823]	9
GO:0005813	centrosome	Cellular Component	IDA[16525022]	71
GO:0070830	tight junction assembly	Biological Process		3
GO:0051297	centrosome organization	Biological Process	IMP[16525022]	5
GO:0051457	maintenance of protein location in nucleus	Biological Process	IDA[18234692]	2
GO:0031116	positive regulation of microtubule polymerization	Biological Process		6
GO:0034260	negative regulation of GTPase activity	Biological Process	IDA[10831612]	4
GO:0019003	GDP binding	Molecular Function		6
GO:0031113	regulation of microtubule polymerization	Biological Process	IMP[16525022]	2
GO:0003924	GTPase activity	Molecular Function	IMP[10831612]	41
GO:0005515	protein binding	Molecular Function	IPI[19368893]	910
GO:0005095	GTPase inhibitor activity	Molecular Function	TAS[10831612]	2
GO:0005634	nucleus	Cellular Component	IDA[18234692]	770
GO:0005525	GTP binding	Molecular Function	IMP[10831612]	53

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with ARL2 (count: 10)

Gene Symbol	Pathway Count	Pathway List
APC	6	lateral plasma membrane; centrosome; tight junction assembly; positive regulation of microtubule polymerization; protein binding; nucleus;
RAB14	6	small GTPase mediated signal transduction; GTP catabolic process; GDP binding; GTPase activity; protein binding; GTP binding;
RAB6C	6	small GTPase mediated signal transduction; GTP catabolic process; centrosome; GTPase activity; nucleus; GTP binding;
SEPT5	5	cell cycle; GTP catabolic process; GTPase activity; protein binding; GTP binding;
ARF6	5	small GTPase mediated signal transduction; GTP catabolic process; GTPase activity; protein binding; GTP binding;
RAB27A	5	small GTPase mediated signal transduction; GDP binding; GTPase activity; protein binding; GTP binding;
RAB2A	5	small GTPase mediated signal transduction; GTP catabolic process; GDP binding; GTPase activity; GTP binding;
RAB6A	5	small GTPase mediated signal transduction; GTP catabolic process; GTPase activity; protein binding; GTP binding;
EFTUD2	5	GTP catabolic process; GTPase activity; protein binding; nucleus; GTP binding;
OPA1	5	GTP catabolic process; mitochondrial intermembrane space; GTPase activity; protein binding; GTP binding;

Genes shared at least 2 KEGG pathways with ARL2 (count: 0)

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Region: chr11:64781585..64789656 View in gBrowse