ADHDgene Database

Gene Report

Basic Info

Approved Symbol	AGAP3
Previous Symbol	CENTG3
Approved Name	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3
Previous Name	centaurin, gamma 3
Location	7q36.1
Position	chr7:150782918-150841523, +
External Links	HGNC: 16923 Entrez Gene: 116988 Ensembl: ENSG00000133612 UCSC: uc003wjg.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 7)

rs_ID	Location	Functional Annotation
rs4725391	Chr7:150805137(Fwd)	intron_variant; nc_transcript_variant; upstream_gene_variant
rs10279150	Chr7:150789761(Fwd)	intron_variant; nc_transcript_variant
rs10279252	Chr7:150789791(Fwd)	intron_variant; nc_transcript_variant
rs4517031	Chr7:150796927(Fwd)	intron_variant; nc_transcript_variant
rs4440544	Chr7:150797234(Fwd)	intron_variant; nc_transcript_variant
rs4725390	Chr7:150805082(Fwd)	intron_variant; nc_transcript_variant; upstream_gene_variant
rs4725991	Chr7:150801238(Fwd)	intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005634	nucleus	Cellular Component	770
GO:0005737	cytoplasm	Cellular Component	690
GO:0005525	GTP binding	Molecular Function	53
GO:0005543	phospholipid binding	Molecular Function	61
GO:0008270	zinc ion binding	Molecular Function	323
GO:0016020	membrane	Cellular Component	139
GO:0007264	small GTPase mediated signal transduction	Biological Process	58
GO:0008060	ARF GTPase activator activity	Molecular Function	4
GO:0000060	protein import into nucleus, translocation	Biological Process	5
GO:0003924	GTPase activity	Molecular Function	41
GO:0043161	proteasomal ubiquitin-dependent protein catabolic process	Biological Process	16
GO:0034614	cellular response to reactive oxygen species	Biological Process	5
GO:0032312	regulation of ARF GTPase activity	Biological Process	4
GO:0031593	polyubiquitin binding	Molecular Function	4
GO:0071944	cell periphery	Cellular Component	2

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with AGAP3 (count: 3)

Gene Symbol	Pathway Count	Pathway List
RAB6C	5	nucleus; cytoplasm; GTP binding; small GTPase mediated signal transduction; GTPase activity;
RNF112	5	nucleus; cytoplasm; GTP binding; zinc ion binding; GTPase activity;
ARHGAP5	5	cytoplasm; GTP binding; membrane; small GTPase mediated signal transduction; GTPase activity;

Genes shared at least 2 KEGG pathways with AGAP3 (count: 0)

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Region: chr7:150782918..150841523 View in gBrowse