ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0008543
Name fibroblast growth factor receptor signaling pathway
Type biological process
No. of Genes in ADHDgene  33
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 33)

Literature-origin genes (count: 4)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FGF12 fibroblast growth factor 12 3q28 1(0/1/0) IDA[12815063]
GSK3B glycogen synthase kinase 3 beta 3q13.3 1(1/0/0) TAS
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) TAS
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) TAS

Genes from other sources Help (count: 29)

Approved Symbol Approved Name Source Evidence[PMID]
BAD BCL2-associated agonist of cell death Mapped by significant region TAS
MAPK3 mitogen-activated protein kinase 3 Mapped by CNV TAS
FGF9 fibroblast growth factor 9 Mapped by significant region IGI[8663044]; TAS
FGF4 fibroblast growth factor 4 Mapped by significant region IGI[8663044]; TAS
SHOC2 soc-2 suppressor of clear homolog (C. elegans) Mapped by LD-proxy NAS[9618511]
PRKAR2B protein kinase, cAMP-dependent, regulatory, type II, beta Mapped by CNV TAS
RPS6KB2 ribosomal protein S6 kinase, 70kDa, polypeptide 2 Mapped by significant region TAS
ADCY9 adenylate cyclase 9 Mapped by significant region TAS
FGF3 fibroblast growth factor 3 Mapped by significant region IGI[8663044]; TAS
MAPK1 mitogen-activated protein kinase 1 Mapped by LD-proxy TAS
MAPKAP1 mitogen-activated protein kinase associated protein 1 Mapped by significant region TAS
CEP57 centrosomal protein 57kDa Mapped by significant region IPI[12717444]
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase Mapped by significant region TAS
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway ISS
PDPK1 3-phosphoinositide dependent protein kinase-1 Mapped by significant region TAS
ADCY3 adenylate cyclase 3 Mapped by LD-proxy TAS
MLST8 MTOR associated protein, LST8 homolog (S. cerevisiae) Mapped by significant region TAS
UBC ubiquitin C Mapped by CNV TAS
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region TAS
TSC2 tuberous sclerosis 2 Mapped by significant region TAS
FIBP fibroblast growth factor (acidic) intracellular binding protein Mapped by significant region TAS[9806903]
ITPR1 inositol 1,4,5-trisphosphate receptor, type 1 Mapped by CNV TAS
PIK3R1 phosphoinositide-3-kinase, regulatory subunit 1 (alpha) Mapped by significant region TAS
ADCY4 adenylate cyclase 4 Mapped by significant region TAS
CTGF connective tissue growth factor Mapped by significant region IEA
RICTOR RPTOR independent companion of MTOR, complex 2 Mapped by significant region TAS
ITPR2 inositol 1,4,5-trisphosphate receptor, type 2 Mapped by Literature SNP TAS
FGF19 fibroblast growth factor 19 Mapped by significant region IGI[18187602]; IPI[10525310]; TAS
UBB ubiquitin B Mapped by significant region TAS