ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	GABARAPL2
Symbol Alias	GEF2, ATG8, GATE16, GATE-16, ATG8C
Approved Name	GABA(A) receptor-associated protein-like 2
Location	16q22.1
Position	chr16:75600249-75611779, +
External Links	HGNC: 13291 Entrez Gene: 11345 Ensembl: ENSG00000034713 UCSC: uc002fen.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 19)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 19)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000139	Golgi membrane	Cellular Component	ISS[11414770]	95
GO:0000421	autophagic vacuole membrane	Cellular Component	IDA[15169837]	4
GO:0000149	SNARE binding	Molecular Function	ISS[10747018]	6
GO:0005622	intracellular	Cellular Component		67
GO:0005515	protein binding	Molecular Function		910
GO:0005776	autophagic vacuole	Cellular Component		4
GO:0005737	cytoplasm	Cellular Component		690
GO:0005829	cytosol	Cellular Component	ISS[11414770]	447
GO:0005794	Golgi apparatus	Cellular Component	ISS[11414770]	157
GO:0006891	intra-Golgi vesicle-mediated transport	Biological Process	ISS[10747018]	13
GO:0006914	autophagy	Biological Process	NAS[12507496]	13
GO:0008017	microtubule binding	Molecular Function	NAS[11414770]	32
GO:0015031	protein transport	Biological Process		75
GO:0031410	cytoplasmic vesicle	Cellular Component		20
GO:0032781	positive regulation of ATPase activity	Biological Process	ISS[10747018]	3
GO:0042177	negative regulation of protein catabolic process	Biological Process		5
GO:0048487	beta-tubulin binding	Molecular Function		4
GO:0050811	GABA receptor binding	Molecular Function	NAS[11414770]	3
GO:0051117	ATPase binding	Molecular Function	ISS[10747018]	7

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04140	Regulation of autophagy	6

Genes shared at least 5 GO terms with GABARAPL2 (count: 16)

Gene Symbol	Pathway Count	Pathway List
ARRB1	6	Golgi membrane; protein binding; cytoplasm; cytosol; protein transport; cytoplasmic vesicle;
COG5	6	Golgi membrane; protein binding; cytosol; Golgi apparatus; intra-Golgi vesicle-mediated transport; protein transport;
MAP1LC3B	6	autophagic vacuole membrane; intracellular; protein binding; autophagic vacuole; autophagy; cytoplasmic vesicle;
SNCA	6	protein binding; cytoplasm; cytosol; Golgi apparatus; microtubule binding; beta-tubulin binding;
GOPC	5	Golgi membrane; protein binding; cytoplasm; Golgi apparatus; protein transport;
RAB14	5	Golgi membrane; intracellular; protein binding; cytosol; protein transport;
RAB6A	5	Golgi membrane; protein binding; cytosol; Golgi apparatus; cytoplasmic vesicle;
STX16	5	Golgi membrane; protein binding; cytoplasm; Golgi apparatus; intra-Golgi vesicle-mediated transport;
YKT6	5	Golgi membrane; cytoplasm; cytosol; Golgi apparatus; protein transport;
ATG9A	5	autophagic vacuole membrane; protein binding; Golgi apparatus; protein transport; cytoplasmic vesicle;
ARRB2	5	protein binding; cytoplasm; cytosol; protein transport; cytoplasmic vesicle;
CDK5RAP2	5	protein binding; cytoplasm; cytosol; Golgi apparatus; microtubule binding;
CEP57	5	protein binding; cytoplasm; cytosol; Golgi apparatus; microtubule binding;
CRYAB	5	protein binding; cytoplasm; cytosol; Golgi apparatus; microtubule binding;
HOOK3	5	protein binding; cytoplasm; Golgi apparatus; microtubule binding; protein transport;
SQSTM1	5	protein binding; autophagic vacuole; cytosol; autophagy; cytoplasmic vesicle;

Genes shared at least 2 KEGG pathways with GABARAPL2 (count: 0)

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Region: chr16:75600249..75611779 View in gBrowse