ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0007269
Name neurotransmitter secretion
Type biological process
No. of Genes in ADHDgene  21
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 21)

Literature-origin genes (count: 15)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3p25.3 1(0/1/0) TAS
NRXN1 neurexin 1 2p16.3 1(0/1/0) IEA
MAOA monoamine oxidase A Xp11.4-p11.3 20(13/7/0) TAS
LIN7C lin-7 homolog C (C. elegans) 11p14 1(1/0/0) IEA
STX1A syntaxin 1A (brain) 7q11.2 3(2/1/0) TAS
SYN3 synapsin III 22q12.3 2(1/1/0) IEA
SYT1 synaptotagmin I 12q21.2 4(2/2/0) TAS
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) TAS
SLC5A7 solute carrier family 5 (sodium/choline cotransporter), member 7 2q12 1(1/0/0) TAS
CPLX1 complexin 1 4p16.3 1(1/0/0) TAS
NRXN3 neurexin 3 14q31 1(0/1/0) IEA
SYT2 synaptotagmin II 1q32.1 1(1/0/0) TAS
VAMP2 vesicle-associated membrane protein 2 (synaptobrevin 2) 17p13.1 2(0/2/0) TAS
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) NAS; TAS
SNPH syntaphilin 20p13 1(1/0/0) NAS[10707983]

Genes from other sources Help (count: 6)

Approved Symbol Approved Name Source Evidence[PMID]
BAIAP3 BAI1-associated protein 3 Mapped by significant region TAS[9790924]
SYT4 synaptotagmin IV Mapped by significant region IEA
ABAT 4-aminobutyrate aminotransferase Mapped by significant region TAS
HSPA8 heat shock 70kDa protein 8 Mapped by significant region TAS
RAB14 RAB14, member RAS oncogene family Mapped by significant region; Mapped by PBA pathway NAS
NRXN2 neurexin 2 Mapped by significant region IEA