ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	USE1
Symbol Alias	p31, SLT1, MDS032
Approved Name	unconventional SNARE in the ER 1 homolog (S. cerevisiae)
Name Alias	Q-SNARE, "SNARE-like tail-anchored protein 1 homolog (S. cerevisiae)"
Location	19p13.11
Position	chr19:17326155-17330638, +
External Links	HGNC: 30882 Entrez Gene: 55850 Ensembl: ENSG00000053501 UCSC: uc002nfo.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by PBA pathway

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 1)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0048193	Golgi vesicle transport	Biological Process		49

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005783	endoplasmic reticulum	Cellular Component	IDA[15029241]	100
GO:0005764	lysosome	Cellular Component	ISS[16354670]	31
GO:0006888	ER to Golgi vesicle-mediated transport	Biological Process	ISS[16354670]	24
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0015031	protein transport	Biological Process		75
GO:0007041	lysosomal transport	Biological Process	ISS[16354670]	2
GO:0030163	protein catabolic process	Biological Process	ISS[16354670]	5
GO:0016021	integral to membrane	Cellular Component		845
GO:0005515	protein binding	Molecular Function	IPI[15272311]	910
GO:0060628	regulation of ER to Golgi vesicle-mediated transport	Biological Process		2
GO:0071786	endoplasmic reticulum tubular network organization	Biological Process		4
GO:0032940	secretion by cell	Biological Process	ISS[16354670]	2

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04130	SNARE interactions in vesicular transport	20

Genes shared at least 5 GO terms with USE1 (count: 12)

Gene Symbol	Pathway Count	Pathway List
SEC22C	6	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; integral to membrane; Golgi vesicle transport;
STX18	6	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; integral to membrane; protein binding; Golgi vesicle transport;
TMED10	6	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; integral to membrane; protein binding; Golgi vesicle transport;
ZW10	6	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; protein binding; Golgi vesicle transport;
BET1	6	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; integral to membrane; protein binding; Golgi vesicle transport;
SEC22B	6	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; integral to membrane; protein binding; Golgi vesicle transport;
NPC1	5	endoplasmic reticulum; lysosome; lysosomal transport; integral to membrane; protein binding;
TMED2	5	endoplasmic reticulum; ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; integral to membrane; protein binding;
ERGIC1	5	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; integral to membrane; protein binding; Golgi vesicle transport;
LMAN1	5	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; integral to membrane; protein binding; Golgi vesicle transport;
LMAN2L	5	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; integral to membrane; Golgi vesicle transport;
SEC22A	5	ER to Golgi vesicle-mediated transport; endoplasmic reticulum membrane; protein transport; integral to membrane; Golgi vesicle transport;

Genes shared at least 2 KEGG pathways with USE1 (count: 0)

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Region: chr19:17326155..17330638 View in gBrowse