ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PRCP
Symbol Alias	PCP, HUMPCP
Approved Name	prolylcarboxypeptidase (angiotensinase C)
Location	11q14
Position	chr11:82534544-82681626, -
External Links	HGNC: 9344 Entrez Gene: 5547 Ensembl: ENSG00000137509 UCSC: uc001ozs.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 7)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005886	plasma membrane	Cellular Component	772
GO:0006508	proteolysis	Biological Process	102
GO:0007596	blood coagulation	Biological Process	83
GO:0007597	blood coagulation, intrinsic pathway	Biological Process	4
GO:0004185	serine-type carboxypeptidase activity	Molecular Function	2
GO:0005515	protein binding	Molecular Function	910
GO:0005764	lysosome	Cellular Component	31

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa04974	Protein digestion and absorption	10	Protein is a dietary component essential for nutritional hom...... Protein is a dietary component essential for nutritional homeostasis in humans. Normally, ingested protein undergoes a complex series of degradative processes following the action of gastric, pancreatic and small intestinal enzymes. The result of this proteolytic activity is a mixture of amino acids and small peptides. Amino acids (AAs) are transported into the enterocyte (intestinal epithelial cell) by a variety of AA transporters that are specific for cationic (basic) AA, neutral AA, and anionic (acidic) AA. Small peptides are absorbed into enterocytes by the PEPT1 transporter. Inside enterocytes peptides are hydrolyzed, and the resulting amino acids are released together with those absorbed by AA transporters into blood via multiple, basolateral, AA transporters. Hydrolysis-resistant peptides, however, are transported out of the cells by a basolateral peptide transporter that has not been identified molecularly. More...

Genes shared at least 5 GO terms with PRCP (count: 1)

Gene Symbol	Pathway Count	Pathway List
F10	5	plasma membrane; proteolysis; blood coagulation; blood coagulation, intrinsic pathway; protein binding;

Genes shared at least 2 KEGG pathways with PRCP (count: 0)

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Region: chr11:82534544..82681626 View in gBrowse