ADHDgene Database

Gene Report

Basic Info

Approved Symbol	NEU3
Approved Name	sialidase 3 (membrane sialidase)
Location	11q13.5
Position	chr11:74699179-74729938, +
External Links	HGNC: 7760 Entrez Gene: 10825 Ensembl: ENSG00000162139 UCSC: uc001ovw.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005975	carbohydrate metabolic process	Biological Process	IDA[12730204]	50
GO:0005887	integral to plasma membrane	Cellular Component	TAS[10405317]	220
GO:0006665	sphingolipid metabolic process	Biological Process		16
GO:0006644	phospholipid metabolic process	Biological Process		59
GO:0005886	plasma membrane	Cellular Component	IDA[12730204]	772
GO:0003824	catalytic activity	Molecular Function	TAS[10405317]	15
GO:0052795	exo-alpha-(2->6)-sialidase activity	Molecular Function		1
GO:0052794	exo-alpha-(2->3)-sialidase activity	Molecular Function		1
GO:0052796	exo-alpha-(2->8)-sialidase activity	Molecular Function		1
GO:0006689	ganglioside catabolic process	Biological Process	TAS[10405317]	1
GO:0006687	glycosphingolipid metabolic process	Biological Process		9
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0016997	alpha-sialidase activity	Molecular Function	IDA[12730204]	1

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00600	Sphingolipid metabolism	10
hsa00511	Other glycan degradation	1

Genes shared at least 5 GO terms with NEU3 (count: 4)

Gene Symbol	Pathway Count	Pathway List
SMPD2	6	integral to plasma membrane; sphingolipid metabolic process; phospholipid metabolic process; plasma membrane; glycosphingolipid metabolic process; small molecule metabolic process;
PRKD1	5	integral to plasma membrane; sphingolipid metabolic process; phospholipid metabolic process; plasma membrane; small molecule metabolic process;
ENPP7	5	sphingolipid metabolic process; phospholipid metabolic process; plasma membrane; glycosphingolipid metabolic process; small molecule metabolic process;
STS	5	sphingolipid metabolic process; phospholipid metabolic process; plasma membrane; glycosphingolipid metabolic process; small molecule metabolic process;

Genes shared at least 2 KEGG pathways with NEU3 (count: 0)

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Region: chr11:74699179..74729938 View in gBrowse