ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	B4GALT4
Symbol Alias	beta4Gal-T4
Approved Name	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 4
Location	3q13.3
Position	chr3:118930579-118959950, -
External Links	HGNC: 927 Entrez Gene: 8702 Ensembl: ENSG00000121578 UCSC: uc003eci.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by CNV

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 2)

ID	Location	Size	Band	Type	Inheritance
CNV_Elia[2010]_32	chr3:120389132-120430845 (NCBI Build 35 (hg17))	41714	3q13.32	Deletion (hemizygous)	Paternal
CNV_Elia[2010]_33	chr3:120389132-120430845 (NCBI Build 35 (hg17))	41714	3q13.32	Deletion (hemizygous)	Paternal

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0000139	Golgi membrane	Cellular Component		95
GO:0003945	N-acetyllactosamine synthase activity	Molecular Function		1
GO:0005975	carbohydrate metabolic process	Biological Process		50
GO:0006643	membrane lipid metabolic process	Biological Process	TAS[9792633]	1
GO:0008378	galactosyltransferase activity	Molecular Function	TAS[9792633]	3
GO:0016021	integral to membrane	Cellular Component		845
GO:0018146	keratan sulfate biosynthetic process	Biological Process		8
GO:0018279	protein N-linked glycosylation via asparagine	Biological Process		24
GO:0030203	glycosaminoglycan metabolic process	Biological Process		20
GO:0032580	Golgi cisterna membrane	Cellular Component		18
GO:0042339	keratan sulfate metabolic process	Biological Process		9
GO:0043687	post-translational protein modification	Biological Process		37
GO:0044267	cellular protein metabolic process	Biological Process		64
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0046872	metal ion binding	Molecular Function		170

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3	Keratan sulfate (KS) is a glycosaminoglycan with the basic d...... Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure. More...
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5
hsa01100	Metabolic pathways	237

Genes shared at least 5 GO terms with B4GALT4 (count: 24)

Gene Symbol	Pathway Count	Pathway List
B4GALT6	13	Golgi membrane; carbohydrate metabolic process; galactosyltransferase activity; integral to membrane; keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; glycosaminoglycan metabolic process; Golgi cisterna membrane; keratan sulfate metabolic process; post-translational protein modification; cellular protein metabolic process; small molecule metabolic process; metal ion binding;
ST3GAL4	10	Golgi membrane; carbohydrate metabolic process; keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; glycosaminoglycan metabolic process; Golgi cisterna membrane; keratan sulfate metabolic process; post-translational protein modification; cellular protein metabolic process; small molecule metabolic process;
CHPF	7	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; Golgi cisterna membrane; small molecule metabolic process; metal ion binding;
CHST5	7	Golgi membrane; carbohydrate metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process;
CHST6	7	Golgi membrane; carbohydrate metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process;
MGAT1	7	Golgi membrane; carbohydrate metabolic process; integral to membrane; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; metal ion binding;
B3GAT1	6	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process; metal ion binding;
B3GNT1	6	Golgi membrane; carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process;
LMAN1	6	Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; metal ion binding;
MAN2A2	6	Golgi membrane; carbohydrate metabolic process; integral to membrane; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process;
MGAT4B	6	Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process; metal ion binding;
B3GAT3	5	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process;
B3GNT6	5	Golgi membrane; galactosyltransferase activity; integral to membrane; post-translational protein modification; cellular protein metabolic process;
CHST9	5	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process;
DSE	5	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process;
FURIN	5	Golgi membrane; integral to membrane; post-translational protein modification; cellular protein metabolic process; metal ion binding;
GALNT1	5	Golgi membrane; integral to membrane; Golgi cisterna membrane; post-translational protein modification; cellular protein metabolic process;
HS3ST2	5	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process;
HS3ST5	5	Golgi membrane; carbohydrate metabolic process; integral to membrane; glycosaminoglycan metabolic process; small molecule metabolic process;
MAN1A1	5	Golgi membrane; integral to membrane; protein N-linked glycosylation via asparagine; post-translational protein modification; cellular protein metabolic process;
GALNS	5	carbohydrate metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; metal ion binding;
OGN	5	carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process;
OMD	5	carbohydrate metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process;
STS	5	integral to membrane; post-translational protein modification; cellular protein metabolic process; small molecule metabolic process; metal ion binding;

Genes shared at least 2 KEGG pathways with B4GALT4 (count: 4)

Gene Symbol	Pathway Count	Pathway List
B3GNT1	3	Glycosaminoglycan biosynthesis - keratan sulfate; Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
FUT4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
GCNT2	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
ST3GAL4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;

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Region: chr3:118930579..118959950 View in gBrowse