ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	B3GNT1
Previous Symbol	B3GNT6
Symbol Alias	iGNT, iGAT, iGnT, BETA3GNTI, B3GN-T1
Approved Name	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 1
Previous Name	UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6
Location	11q13.2
Position	chr11:66112843-66115163, -
External Links	HGNC: 15685 Entrez Gene: 11041 Ensembl: ENSG00000174684 UCSC: uc001ohr.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0018146	keratan sulfate biosynthetic process	Biological Process		8
GO:0008532	N-acetyllactosaminide beta-1,3-N-acetylglucosaminyltransferase activity	Molecular Function	IDA[9405606]	1
GO:0030203	glycosaminoglycan metabolic process	Biological Process		20
GO:0030173	integral to Golgi membrane	Cellular Component	NAS[9405606]	8
GO:0042339	keratan sulfate metabolic process	Biological Process		9
GO:0030311	poly-N-acetyllactosamine biosynthetic process	Biological Process	IDA[9405606]	1
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0000139	Golgi membrane	Cellular Component		95
GO:0006486	protein glycosylation	Biological Process		15
GO:0005975	carbohydrate metabolic process	Biological Process		50

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3	Keratan sulfate (KS) is a glycosaminoglycan with the basic d...... Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure. More...
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5
hsa01100	Metabolic pathways	237

Genes shared at least 5 GO terms with B3GNT1 (count: 9)

Gene Symbol	Pathway Count	Pathway List
ST3GAL4	7	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; integral to Golgi membrane; keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process;
B4GALT4	6	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process;
B4GALT6	6	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process;
CHST5	6	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process;
CHST6	6	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; Golgi membrane; carbohydrate metabolic process;
OGN	5	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; carbohydrate metabolic process;
OMD	5	keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process; small molecule metabolic process; carbohydrate metabolic process;
B3GAT1	5	glycosaminoglycan metabolic process; small molecule metabolic process; Golgi membrane; protein glycosylation; carbohydrate metabolic process;
B3GAT3	5	glycosaminoglycan metabolic process; small molecule metabolic process; Golgi membrane; protein glycosylation; carbohydrate metabolic process;

Genes shared at least 2 KEGG pathways with B3GNT1 (count: 4)

Gene Symbol	Pathway Count	Pathway List
B4GALT4	3	Glycosaminoglycan biosynthesis - keratan sulfate; Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
FUT4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
GCNT2	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
ST3GAL4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;

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Region: chr11:66112843..66115163 View in gBrowse