ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	CHST6
Previous Symbol	MCDC1
Approved Name	carbohydrate (N-acetylglucosamine 6-O) sulfotransferase 6
Location	16q22
Position	chr16:75507022-75529282, -
External Links	HGNC: 6938 Entrez Gene: 4166 Ensembl: ENSG00000183196 UCSC: uc002fef.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
16q23.1-24.3	chr16:74100000-90354753	1 (1/0/0)

Gene related GO terms (count: 11)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0042339	keratan sulfate metabolic process	Biological Process		9
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0006790	sulfur compound metabolic process	Biological Process	IDA[11352640]	4
GO:0016021	integral to membrane	Cellular Component		845
GO:0018146	keratan sulfate biosynthetic process	Biological Process	IDA[11278593]	8
GO:0030203	glycosaminoglycan metabolic process	Biological Process		20
GO:0005794	Golgi apparatus	Cellular Component	TAS[11181564]	157
GO:0001517	N-acetylglucosamine 6-O-sulfotransferase activity	Molecular Function	IDA[11278593]; TAS[11181564]	2
GO:0006044	N-acetylglucosamine metabolic process	Biological Process	IC[11181564]; IDA[11352640]	2
GO:0005975	carbohydrate metabolic process	Biological Process		50
GO:0000139	Golgi membrane	Cellular Component		95

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00533	Glycosaminoglycan biosynthesis - keratan sulfate	3	Keratan sulfate (KS) is a glycosaminoglycan with the basic d...... Keratan sulfate (KS) is a glycosaminoglycan with the basic disaccharide unit of N-acetyllactosamine, Gal(b1-4)GlcNAc(b1-3), with sulfate esters at C-6 of GlcNAc and Gal residues. There are two types of KS distinguished by the protein linkage: type I for N-linked via the N-glycan core structure and type II for O-linked via the O-glycan core 2 structure. More...

Genes shared at least 5 GO terms with CHST6 (count: 14)

Gene Symbol	Pathway Count	Pathway List
CHST5	11	keratan sulfate metabolic process; small molecule metabolic process; sulfur compound metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; Golgi apparatus; N-acetylglucosamine 6-O-sulfotransferase activity; N-acetylglucosamine metabolic process; carbohydrate metabolic process; Golgi membrane;
B4GALT4	7	keratan sulfate metabolic process; small molecule metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
B4GALT6	7	keratan sulfate metabolic process; small molecule metabolic process; integral to membrane; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
B3GNT1	6	keratan sulfate metabolic process; small molecule metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
ST3GAL4	6	keratan sulfate metabolic process; small molecule metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
B3GAT3	6	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; Golgi apparatus; carbohydrate metabolic process; Golgi membrane;
CHST9	6	small molecule metabolic process; sulfur compound metabolic process; integral to membrane; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
DSE	6	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; Golgi apparatus; carbohydrate metabolic process; Golgi membrane;
OGN	5	keratan sulfate metabolic process; small molecule metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process;
OMD	5	keratan sulfate metabolic process; small molecule metabolic process; keratan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process;
B3GAT1	5	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
CHPF	5	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
HS3ST2	5	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;
HS3ST5	5	small molecule metabolic process; integral to membrane; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi membrane;

Genes shared at least 2 KEGG pathways with CHST6 (count: 0)

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Region: chr16:75507022..75529282 View in gBrowse