ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ST3GAL4
Previous Symbol	CGS23, SIAT4, NANTA3, SIAT4C
Symbol Alias	STZ, SAT3, FLJ11867
Approved Name	ST3 beta-galactoside alpha-2,3-sialyltransferase 4
Previous Name	sialyltransferase 4C (beta-galactosidase alpha-2,3-sialytransferase)
Name Alias	ST3Gal IV
Location	11q23-q24
Position	chr11:126225535-126310533, +
External Links	HGNC: 10864 Entrez Gene: 6484 Ensembl: ENSG00000110080 UCSC: uc001qdu.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 15)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 15)

ID	Name	Type	No. of Genes in ADHDgene
GO:0016266	O-glycan processing	Biological Process	5
GO:0018146	keratan sulfate biosynthetic process	Biological Process	8
GO:0018279	protein N-linked glycosylation via asparagine	Biological Process	24
GO:0030173	integral to Golgi membrane	Cellular Component	8
GO:0000139	Golgi membrane	Cellular Component	95
GO:0003836	beta-galactoside (CMP) alpha-2,3-sialyltransferase activity	Molecular Function	1
GO:0005576	extracellular region	Cellular Component	240
GO:0005975	carbohydrate metabolic process	Biological Process	50
GO:0044267	cellular protein metabolic process	Biological Process	64
GO:0044281	small molecule metabolic process	Biological Process	248
GO:0047288	monosialoganglioside sialyltransferase activity	Molecular Function	1
GO:0030203	glycosaminoglycan metabolic process	Biological Process	20
GO:0032580	Golgi cisterna membrane	Cellular Component	18
GO:0042339	keratan sulfate metabolic process	Biological Process	9
GO:0043687	post-translational protein modification	Biological Process	37

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5
hsa01100	Metabolic pathways	237

Genes shared at least 5 GO terms with ST3GAL4 (count: 13)

Gene Symbol	Pathway Count	Pathway List
B4GALT4	10	keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; Golgi membrane; carbohydrate metabolic process; cellular protein metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; Golgi cisterna membrane; keratan sulfate metabolic process; post-translational protein modification;
B4GALT6	10	keratan sulfate biosynthetic process; protein N-linked glycosylation via asparagine; Golgi membrane; carbohydrate metabolic process; cellular protein metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; Golgi cisterna membrane; keratan sulfate metabolic process; post-translational protein modification;
B3GNT1	7	keratan sulfate biosynthetic process; integral to Golgi membrane; Golgi membrane; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process;
GALNT1	6	O-glycan processing; Golgi membrane; extracellular region; cellular protein metabolic process; Golgi cisterna membrane; post-translational protein modification;
CHST5	6	keratan sulfate biosynthetic process; Golgi membrane; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process;
CHST6	6	keratan sulfate biosynthetic process; Golgi membrane; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process;
OGN	6	keratan sulfate biosynthetic process; extracellular region; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process;
OMD	6	keratan sulfate biosynthetic process; extracellular region; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; keratan sulfate metabolic process;
MAN2A2	5	protein N-linked glycosylation via asparagine; Golgi membrane; carbohydrate metabolic process; cellular protein metabolic process; post-translational protein modification;
MGAT1	5	protein N-linked glycosylation via asparagine; Golgi membrane; carbohydrate metabolic process; cellular protein metabolic process; post-translational protein modification;
ST8SIA3	5	protein N-linked glycosylation via asparagine; integral to Golgi membrane; Golgi membrane; cellular protein metabolic process; post-translational protein modification;
CHPF	5	Golgi membrane; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process; Golgi cisterna membrane;
CHST9	5	Golgi membrane; extracellular region; carbohydrate metabolic process; small molecule metabolic process; glycosaminoglycan metabolic process;

Genes shared at least 2 KEGG pathways with ST3GAL4 (count: 4)

Gene Symbol	Pathway Count	Pathway List
B3GNT1	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
B4GALT4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
FUT4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
GCNT2	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;

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Region: chr11:126225535..126310533 View in gBrowse