ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DSE
Previous Symbol	SART2
Symbol Alias	DSEPI
Approved Name	dermatan sulfate epimerase
Previous Name	"squamous cell carcinoma antigen recognized by T cells 2"
Location	6q22
Position	chr6:116575336-116762424, 1
External Links	HGNC: 21144 Entrez Gene: 29940 Ensembl: ENSG00000111817 UCSC: uc003pws.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
6q22-23	chr6:114600000-139000000	1 (1/0/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0030206	chondroitin sulfate biosynthetic process	biological process	IEA	5
GO:0044281	small molecule metabolic process	biological process	TAS	270
GO:0030208	dermatan sulfate biosynthetic process	biological process	IDA[16505484]; TAS	2
GO:0030203	glycosaminoglycan metabolic process	biological process	TAS	23
GO:0000139	Golgi membrane	cellular component	TAS	106
GO:0005783	endoplasmic reticulum	cellular component	IDA[10679095]	111
GO:0005975	carbohydrate metabolic process	biological process	TAS	59
GO:0015012	heparan sulfate proteoglycan biosynthetic process	biological process	IEA	3
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0005794	Golgi apparatus	cellular component	IDA[10679095]	174
GO:0047757	chondroitin-glucuronate 5-epimerase activity	molecular function	IDA[16505484]	1
GO:0030204	chondroitin sulfate metabolic process	biological process	TAS	9

Gene related KEGG pathways (count: 1)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00532	Chondroitin sulfate biosynthesis	5

Genes shared at least 5 GO terms with DSE (count: 15)

Gene Symbol	Pathway Count	Pathway List
B3GAT3	8	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; heparan sulfate proteoglycan biosynthetic process; integral to membrane; Golgi apparatus; chondroitin sulfate metabolic process;
CHPF	7	chondroitin sulfate biosynthetic process; small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; chondroitin sulfate metabolic process;
CHST9	7	chondroitin sulfate biosynthetic process; small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; chondroitin sulfate metabolic process;
NCAN	6	chondroitin sulfate biosynthetic process; small molecule metabolic process; dermatan sulfate biosynthetic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; chondroitin sulfate metabolic process;
B3GAT1	6	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; chondroitin sulfate metabolic process;
CHST5	6	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; Golgi apparatus;
CHST6	6	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane; Golgi apparatus;
B4GALT6	5	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane;
ARSB	5	small molecule metabolic process; glycosaminoglycan metabolic process; carbohydrate metabolic process; Golgi apparatus; chondroitin sulfate metabolic process;
HS3ST6	5	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane;
SMPD4	5	small molecule metabolic process; Golgi membrane; endoplasmic reticulum; integral to membrane; Golgi apparatus;
HS3ST2	5	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane;
LPCAT1	5	small molecule metabolic process; Golgi membrane; endoplasmic reticulum; integral to membrane; Golgi apparatus;
B4GALT4	5	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane;
HS3ST5	5	small molecule metabolic process; glycosaminoglycan metabolic process; Golgi membrane; carbohydrate metabolic process; integral to membrane;

Genes shared at least 2 KEGG pathways with DSE (count: 0)

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Region: chr6:116575336..116762424 View in gBrowse