ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	FUT4
Previous Symbol	CD15, FCT3A, ELFT
Symbol Alias	FUC-TIV
Approved Name	fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
Name Alias	ELAM ligand fucosyltransferase, "galactoside 3-L-fucosyltransferase"
Location	11q12-qter
Position	chr11:94277017-94283064, +
External Links	HGNC: 4015 Entrez Gene: 2526 Ensembl: ENSG00000196371 UCSC: uc001pez.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006486	protein glycosylation	Biological Process	TAS[11698403]	15
GO:0005975	carbohydrate metabolic process	Biological Process	TAS[1716630]	50
GO:0009986	cell surface	Cellular Component		70
GO:0008417	fucosyltransferase activity	Molecular Function	TAS[1716630]	1
GO:0016021	integral to membrane	Cellular Component		845
GO:0016020	membrane	Cellular Component	TAS[1716630]	139
GO:0036065	fucosylation	Biological Process	TAS[1716630]	1
GO:0032580	Golgi cisterna membrane	Cellular Component		18
GO:0071944	cell periphery	Cellular Component		2
GO:0042355	L-fucose catabolic process	Biological Process	NAS[11698403]	1
GO:0046920	alpha-(1->3)-fucosyltransferase activity	Molecular Function	TAS[11698403]	1
GO:0005794	Golgi apparatus	Cellular Component	TAS[11698403]	157

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa00601	Glycosphingolipid biosynthesis - lacto and neolacto series	5
hsa01100	Metabolic pathways	237
hsa00514	Other types of O-glycan biosynthesis	22	O-mannosyl glycans are a type of O-glycans that are found bo...... O-mannosyl glycans are a type of O-glycans that are found both in eukaryotes and prokaryotes. Biosynthesis of O-mannosyl glycans is initiated by the transfer of mannose from Man-P-Dol to serine or threonine residue, which is catalyzed by protein O-mannosyltransferases POMT1 and POMT2. Defects of these genes are linked to human diseases, such as muscular dystrophies caused by reduced O-mannosylation of alpha-dystroglycan in skeletal muscles [DS:H00120]. More...

Genes shared at least 5 GO terms with FUT4 (count: 0)

Genes shared at least 2 KEGG pathways with FUT4 (count: 23)

Gene Symbol	Pathway Count	Pathway List
B3GNT1	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
B4GALT4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
GCNT2	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
ST3GAL4	2	Glycosphingolipid biosynthesis - lacto and neolacto series; Metabolic pathways;
UGT1A1	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A10	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A3	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A4	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A5	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A6	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A7	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A8	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT1A9	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2A1	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2A2	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2A3	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B10	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B11	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B15	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B17	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B28	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B4	2	Metabolic pathways; Other types of O-glycan biosynthesis;
UGT2B7	2	Metabolic pathways; Other types of O-glycan biosynthesis;

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Region: chr11:94277017..94283064 View in gBrowse