ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	UGT2B17
Approved Name	UDP glucuronosyltransferase 2 family, polypeptide B17
Previous Name	"UDP glycosyltransferase 2 family, polypeptide B17"
Location	4q13
Position	chr4:69402902-69434245, -1
External Links	HGNC: 12547 Entrez Gene: 7367 Ensembl: ENSG00000197888 UCSC: uc021xov.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
4q13.2	chr4:66600000-70500000	1 (1/0/0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0008202	steroid metabolic process	biological process	TAS[8798464]	16
GO:0016020	membrane	cellular component	TAS[8798464]	155
GO:0015020	glucuronosyltransferase activity	molecular function	IEA	20
GO:0005789	endoplasmic reticulum membrane	cellular component	IEA	159
GO:0001972	retinoic acid binding	molecular function	IDA	12
GO:0016021	integral to membrane	cellular component	IEA	932

Gene related KEGG pathways (count: 8)

ID	Name	No. of Genes in ADHDgene
hsa00860	Porphyrin and chlorophyll metabolism	24
hsa00830	Retinol metabolism	19
hsa00040	Pentose and glucuronate interconversions	17
hsa00982	Drug metabolism - cytochrome P450	27
hsa00983	Drug metabolism - other enzymes	22
hsa00980	Metabolism of xenobiotics by cytochrome P450	24
hsa00500	Starch and sucrose metabolism	27
hsa00150	Androgen and estrogen metabolism	24

Genes shared at least 5 GO terms with UGT2B17 (count: 3)

Gene Symbol	Pathway Count	Pathway List
UGT1A8	5	steroid metabolic process; glucuronosyltransferase activity; endoplasmic reticulum membrane; retinoic acid binding; integral to membrane;
UGT2B15	5	steroid metabolic process; glucuronosyltransferase activity; endoplasmic reticulum membrane; retinoic acid binding; integral to membrane;
UGT2B7	5	membrane; glucuronosyltransferase activity; endoplasmic reticulum membrane; retinoic acid binding; integral to membrane;

Genes shared at least 2 KEGG pathways with UGT2B17 (count: 23)

Gene Symbol	Pathway Count	Pathway List
UGT1A10	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B15	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A8	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A4	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A1	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B10	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B28	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A6	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A7	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B7	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B11	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A3	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2B4	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT2A3	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A9	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
UGT1A5	8	Porphyrin and chlorophyll metabolism; Retinol metabolism; Pentose and glucuronate interconversions; Drug metabolism - cytochrome P450; Drug metabolism - other enzymes; Metabolism of xenobiotics by cytochrome P450; Starch and sucrose metabolism; Androgen and estrogen metabolism;
CYP2E1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTT1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTP1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3A1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3B2	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTT2	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
ALDH3B1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;

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Region: chr4:69402902..69434245 View in gBrowse