ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol MAOB
Approved Name monoamine oxidase B
Location Xp11.4-p11.3
Position chrX:43625857-43741721, -
External Links HGNC: 6834
Entrez Gene: 4129
Ensembl: ENSG00000069535
UCSC: uc004dfz.3
No. of Studies 6 (significant: 2; non-significant: 4; trend: 0)
Source Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 6)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Ribases M, 2009(b) Haplotype analysis: P-value=0.0029, OR=1.90 for adult ADHD, specifically associated in the adult ADHD sample. Significant
Li J, 2008 haplotype TCA P-value=0.003, X2=8.71, haplotype CTA P-value=6.978E-19, X2=78.77, haplotype TCG P-value=1.620E-6, X2=23.00, haplotype CTG P-value=6.220E-11, X2=42.75, provides the strongest evidence for the involvement of MAOB gene Significant
Brookes K, 2006 UNPHASED TDT P-value=0.239, global P-value=0.737, no SNP with nominal P-value<0.05 located in this gene Non-significant
Domschke K, 2005 no polymorphism was significantly associated with ADHD Non-significant
Jiang S, 2001 the results showed that ADHD was not in linkage with MAOB gene Non-significant
Lowe N, 2001 there was no significant association with ADHD in this study Non-significant

Gene related SNPs (count: 43)

Literature-origin SNPs (count: 4)

LD-proxies (count: 39)

Gene related CNVs (count: 0)

Gene related other variant (count: 3)

Gene related regions (count: 0)

Gene related GO terms (count: 19)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 19)

Gene related KEGG pathways (count: 8)

Genes shared at least 5 GO terms with MAOB (count: 5)

Genes shared at least 2 KEGG pathways with MAOB (count: 58)

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Region: chrX:43625857..43741721 View in gBrowse
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