ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol ASMT
Approved Name acetylserotonin O-methyltransferase
Location Xp22.3 and Yp11.3
Position chrX:1714348-1761974, +
External Links HGNC: 750
Entrez Gene: 438
Ensembl: ENSG00000196433
UCSC: uc004cqd.2
No. of Studies 1 (significant: 1; non-significant: 0; trend: 0)
Source Literature-origin

Gene related studies (count: 1)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Chaste P, 2011 A splice site mutation in ASMT (IVS5+2T>C) was found and also was detected exclusively in patients with ADHD - for which biochemical analyses indicated that it abolish the activity of ASMT. Significant

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 3)

Gene related regions (count: 0)

Gene related GO terms (count: 10)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 10)

Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with ASMT (count: 1)

Genes shared at least 2 KEGG pathways with ASMT (count: 11)

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Region: chrX:1714348..1761974 View in gBrowse
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