ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

KEGG Pathway Report

Basic Info
ID hsa00350
Name Tyrosine metabolism
No. of Genes in ADHDgene  17
Source Pathway by Database Search

Pathway related genes in ADHDgene (count: 17)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend)
COMT catechol-O-methyltransferase 22q11.21 29(7/22/0)
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0)
MAOA monoamine oxidase A Xp11.4-p11.3 20(13/7/0)
DDC dopa decarboxylase (aromatic L-amino acid decarboxylase) 7p12.1 6(5/1/0)
TH tyrosine hydroxylase 11p15.5 7(2/5/0)
PNMT phenylethanolamine N-methyltransferase 17q 3(2/1/0)
MAOB monoamine oxidase B Xp11.4-p11.3 6(2/4/0)

Genes from other sources Help(count: 10)

Approved Symbol Approved Name Location Source
TRMT11 tRNA methyltransferase 11 homolog (S. cerevisiae) 6q11.1-q22.33 Mapped by significant region
ALDH3B2 aldehyde dehydrogenase 3 family, member B2 11q13 Mapped by significant region
ESCO1 establishment of sister chromatid cohesion N-acetyltransferase 1 18q11.2 Mapped by significant region
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 22q11.23 Mapped by CNV
PNPLA3 patatin-like phospholipase domain containing 3 22q13.31 Mapped by PBA pathway
ALDH3B1 aldehyde dehydrogenase 3 family, member B1 11q13 Mapped by significant region
ALDH3A1 aldehyde dehydrogenase 3 family, member A1 17p11.2 Mapped by significant region
WBSCR22 Williams Beuren syndrome chromosome region 22 7q11.23 Mapped by Literature SNP
LCMT2 leucine carboxyl methyltransferase 2 15q15.3 Mapped by LD-proxy
TYR tyrosinase 11q14.3 Mapped by significant region