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Gene Report
Basic Info
| Approved Symbol | ALDH3B1 |
|---|---|
| Previous Symbol | ALDH7 |
| Approved Name | aldehyde dehydrogenase 3 family, member B1 |
| Name Alias | aldehyde dehydrogenase 7, "aldehyde dehydrogenase 3B1" |
| Location | 11q13 |
| Position | chr11:67776048-67796744, + |
| External Links |
HGNC: 410 Entrez Gene: 221 Ensembl: ENSG00000006534 UCSC: uc001ona.2 |
| No. of Studies | 0 (significant: 0; non-significant: 0; trend: 0) |
| Source | Mapped by significant region |
Gene related studies (count: 0)
Gene related SNPs (count: 0)
Gene related CNVs (count: 0)
Gene related other variant (count: 0)
Gene related regions (count: 1)
| Region Name | Position | No. of Studies (significant/non-significant/trend)  |
|---|---|---|
| 11q | chr11:53700000-135006516 | 2 (1/1/0) |
Gene related GO terms (count: 9)
GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)
GO terms by database search (count: 9)
| ID | Name | Type | Evidence[PMID] | No. of Genes in ADHDgene |
|---|---|---|---|---|
| GO:0006629 | lipid metabolic process | Biological Process | TAS[7828891] | 51 |
| GO:0004030 | aldehyde dehydrogenase [NAD(P)+] activity | Molecular Function | 4 | |
| GO:0034599 | cellular response to oxidative stress | Biological Process | 5 | |
| GO:0005737 | cytoplasm | Cellular Component | 690 | |
| GO:0006066 | alcohol metabolic process | Biological Process | TAS[7828891] | 2 |
| GO:0006068 | ethanol catabolic process | Biological Process | 2 | |
| GO:0004028 | 3-chloroallyl aldehyde dehydrogenase activity | Molecular Function | TAS[7828891] | 3 |
| GO:0046185 | aldehyde catabolic process | Biological Process | 1 | |
| GO:0055114 | oxidation-reduction process | Biological Process | 15 |
Gene related KEGG pathways (count: 8)
| ID | Name | No. of Genes in ADHDgene | Brief Description |
|---|---|---|---|
| hsa01100 | Metabolic pathways | 237 | |
| hsa00410 | beta-Alanine metabolism | 8 | |
| hsa00360 | Phenylalanine metabolism | 8 | |
| hsa00350 | Tyrosine metabolism | 15 | |
| hsa00010 | Glycolysis / Gluconeogenesis | 11 | Glycolysis is the process of converting glucose into pyruvat...... Glycolysis is the process of converting glucose into pyruvate and generating small amounts of ATP (energy) and NADH (reducing power). It is a central pathway that produces important precursor metabolites: six-carbon compounds of glucose-6P and fructose-6P and three-carbon compounds of glycerone-P, glyceraldehyde-3P, glycerate-3P, phosphoenolpyruvate, and pyruvate [MD:M00001]. Acetyl-CoA, another important precursor metabolite, is produced by oxidative decarboxylation of pyruvate [MD:M00307]. When the enzyme genes of this pathway are examined in completely sequenced genomes, the reaction steps of three-carbon compounds from glycerone-P to pyruvate form a conserved core module [MD:M00002], which is found in almost all organisms and which often corresponds to operon structures in bacterial genomes. Gluconeogenesis is a synthesis pathway of glucose from noncarbohydrate precursors. It is essentially a reversal of glycolysis with minor variations of alternative paths [MD:M00003]. More... |
| hsa00982 | Drug metabolism - cytochrome P450 | 29 | |
| hsa00340 | Histidine metabolism | 12 | |
| hsa00980 | Metabolism of xenobiotics by cytochrome P450 | 26 |
Genes shared at least 5 GO terms with ALDH3B1 (count: 1)
| Gene Symbol | Pathway Count | Pathway List |
|---|---|---|
| ALDH3B2 | 5 | lipid metabolic process; aldehyde dehydrogenase [NAD(P)+] activity; alcohol metabolic process; ethanol catabolic process; 3-chloroallyl aldehyde dehydrogenase activity; |
Genes shared at least 2 KEGG pathways with ALDH3B1 (count: 50)
View in gBrowse
Region: chr11:67776048..67796744 View in gBrowse
Copyright: Bioinformatics Lab, Institute of Psychology, Chinese Academy of Sciences Feedback
Last update: Feb 26, 2014