ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	ALDH3B1
Previous Symbol	ALDH7
Approved Name	aldehyde dehydrogenase 3 family, member B1
Name Alias	"aldehyde dehydrogenase 7", "aldehyde dehydrogenase 3B1"
Location	11q13
Position	chr11:67776048-67796744, 1
External Links	HGNC: 410 Entrez Gene: 221 Ensembl: ENSG00000006534 UCSC: uc001ona.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 9)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0006629	lipid metabolic process	biological process	TAS[7828891]	51
GO:0006068	ethanol catabolic process	biological process	IEA	2
GO:0055114	oxidation-reduction process	biological process	IDA	18
GO:0004028	3-chloroallyl aldehyde dehydrogenase activity	molecular function	TAS[7828891]	3
GO:0005737	cytoplasm	cellular component	IDA	781
GO:0046185	aldehyde catabolic process	biological process	IDA	1
GO:0034599	cellular response to oxidative stress	biological process	IDA	7
GO:0006066	alcohol metabolic process	biological process	TAS[7828891]	2
GO:0004030	aldehyde dehydrogenase [NAD(P)+] activity	molecular function	IDA	4

Gene related KEGG pathways (count: 5)

ID	Name	No. of Genes in ADHDgene
hsa00350	Tyrosine metabolism	17
hsa00360	Phenylalanine metabolism	10
hsa00982	Drug metabolism - cytochrome P450	27
hsa00980	Metabolism of xenobiotics by cytochrome P450	24
hsa00340	Histidine metabolism	11

Genes shared at least 5 GO terms with ALDH3B1 (count: 1)

Gene Symbol	Pathway Count	Pathway List
ALDH3B2	5	lipid metabolic process; ethanol catabolic process; 3-chloroallyl aldehyde dehydrogenase activity; alcohol metabolic process; aldehyde dehydrogenase [NAD(P)+] activity;

Genes shared at least 2 KEGG pathways with ALDH3B1 (count: 32)

Gene Symbol	Pathway Count	Pathway List
ALDH3B2	5	Tyrosine metabolism; Phenylalanine metabolism; Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450; Histidine metabolism;
ALDH3A1	5	Tyrosine metabolism; Phenylalanine metabolism; Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450; Histidine metabolism;
MAOA	4	Tyrosine metabolism; Phenylalanine metabolism; Drug metabolism - cytochrome P450; Histidine metabolism;
MAOB	4	Tyrosine metabolism; Phenylalanine metabolism; Drug metabolism - cytochrome P450; Histidine metabolism;
DDC	3	Tyrosine metabolism; Phenylalanine metabolism; Histidine metabolism;
TRMT11	2	Tyrosine metabolism; Histidine metabolism;
ESCO1	2	Tyrosine metabolism; Phenylalanine metabolism;
WBSCR22	2	Tyrosine metabolism; Histidine metabolism;
LCMT2	2	Tyrosine metabolism; Histidine metabolism;
PNPLA3	2	Tyrosine metabolism; Phenylalanine metabolism;
MIF	2	Tyrosine metabolism; Phenylalanine metabolism;
UGT2B10	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B7	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
CYP2E1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A4	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B28	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A3	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTT1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B15	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTP1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2A3	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A7	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A10	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A5	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A8	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B4	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B17	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A9	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A1	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT1A6	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
GSTT2	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;
UGT2B11	2	Drug metabolism - cytochrome P450; Metabolism of xenobiotics by cytochrome P450;

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Region: chr11:67776048..67796744 View in gBrowse