ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol PNMT
Previous Symbol PENT
Approved Name phenylethanolamine N-methyltransferase
Location 17q
Position chr17:37824234-37826728, +
External Links HGNC: 9160
Entrez Gene: 5409
Ensembl: ENSG00000141744
UCSC: uc002hsi.1
No. of Studies 3 (significant: 2; non-significant: 1; trend: 0)
Source Literature-origin; Mapped by LD-proxy; Mapped by literature SNP

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Brookes K, 2006 UNPHASED TDT P-value=0.0078, global P-value=0.0134, WHAP TDT P_sum P-value=0.0039; OR=1.67, one or more SNPs with nominal P-value<0.05 located in this gene Significant
Oades RD, 2008 2 SNPs showed significant association Significant
Hawi, Z., 2012 This gene did not show significant association with ADHD. Non-significant

Gene related SNPs (count: 13)

Literature-origin SNPs (count: 5)

LD-proxies (count: 8)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 6)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 6)

Gene related KEGG pathways (count: 2)

Genes shared at least 5 GO terms with PNMT (count: 1)

Genes shared at least 2 KEGG pathways with PNMT (count: 10)

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Region: chr17:37824234..37826728 View in gBrowse
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