ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0032496
Name response to lipopolysaccharide
Type biological process
No. of Genes in ADHDgene  23
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 23)

Literature-origin genes (count: 7)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
TH tyrosine hydroxylase 11p15.5 7(2/5/0) IEA
CNR1 cannabinoid receptor 1 (brain) 6q14-q15 1(1/0/0) IEA
MAOB monoamine oxidase B Xp11.4-p11.3 6(2/4/0) IEA
SNCA synuclein, alpha (non A4 component of amyloid precursor) 4q21.3-q22 1(0/1/0) IDA[12406186]
NGF nerve growth factor (beta polypeptide) 1p13.1 2(2/0/0) IEA
COMT catechol-O-methyltransferase 22q11.21 29(7/22/0) IEA
FGF10 fibroblast growth factor 10 5p13-p12 1(0/1/0) IEA

Genes from other sources Help (count: 16)

Approved Symbol Approved Name Source Evidence[PMID]
IL18BP interleukin 18 binding protein Mapped by significant region IEA
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 Mapped by LD-proxy IEA
SLC11A1 solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 Mapped by significant region ISS
PLCG2 phospholipase C, gamma 2 (phosphatidylinositol-specific) Mapped by significant region IEA
NCF2 neutrophil cytosolic factor 2 Mapped by significant region IEA
TIRAP toll-interleukin 1 receptor (TIR) domain containing adaptor protein Mapped by significant region IDA[11544529]
IL6 interleukin 6 (interferon, beta 2) Mapped by significant region IEA
PTGER4 prostaglandin E receptor 4 (subtype EP4) Mapped by significant region IEA
TJP1 tight junction protein 1 Mapped by CNV; Mapped by significant region IEA
TLR4 toll-like receptor 4 Mapped by significant region IC[16514062]; IDA[12594207]
CTSG cathepsin G Mapped by significant region IEA
ADAM17 ADAM metallopeptidase domain 17 Mapped by significant region IDA[18383040]
SCGB1A1 secretoglobin, family 1A, member 1 (uteroglobin) Mapped by significant region IEA
EDNRA endothelin receptor type A Mapped by PBA pathway IEA
TNFRSF11A tumor necrosis factor receptor superfamily, member 11a, NFKB activator Mapped by CNV ISS[19940926]
NRF1 nuclear respiratory factor 1 Mapped by LD-proxy IEA