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- Data Summary
GO Report
Basic Info
| ID | GO:0032496 |
|---|---|
| Name | response to lipopolysaccharide |
| Type | biological process |
| No. of Genes in ADHDgene | 23 |
| Source | Pathway by Database Search |
PBA Result (with statistical significance of FDR<0.05)
GO related genes in ADHDgene (count: 23)
Literature-origin genes (count: 7)
| Approved Symbol | Approved Name | Location | No. of Studies (significant/non-significant/trend)  |
Evidence[PMID] |
|---|---|---|---|---|
| TH | tyrosine hydroxylase | 11p15.5 | 7(2/5/0) | IEA |
| CNR1 | cannabinoid receptor 1 (brain) | 6q14-q15 | 1(1/0/0) | IEA |
| MAOB | monoamine oxidase B | Xp11.4-p11.3 | 6(2/4/0) | IEA |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 4q21.3-q22 | 1(0/1/0) | IDA[12406186] |
| NGF | nerve growth factor (beta polypeptide) | 1p13.1 | 2(2/0/0) | IEA |
| COMT | catechol-O-methyltransferase | 22q11.21 | 29(7/22/0) | IEA |
| FGF10 | fibroblast growth factor 10 | 5p13-p12 | 1(0/1/0) | IEA |
Genes from other sources (count: 16)
| Approved Symbol | Approved Name | Source | Evidence[PMID] |
|---|---|---|---|
| IL18BP | interleukin 18 binding protein | Mapped by significant region | IEA |
| UGT1A1 | UDP glucuronosyltransferase 1 family, polypeptide A1 | Mapped by LD-proxy | IEA |
| SLC11A1 | solute carrier family 11 (proton-coupled divalent metal ion transporter), member 1 | Mapped by significant region | ISS |
| PLCG2 | phospholipase C, gamma 2 (phosphatidylinositol-specific) | Mapped by significant region | IEA |
| NCF2 | neutrophil cytosolic factor 2 | Mapped by significant region | IEA |
| TIRAP | toll-interleukin 1 receptor (TIR) domain containing adaptor protein | Mapped by significant region | IDA[11544529] |
| IL6 | interleukin 6 (interferon, beta 2) | Mapped by significant region | IEA |
| PTGER4 | prostaglandin E receptor 4 (subtype EP4) | Mapped by significant region | IEA |
| TJP1 | tight junction protein 1 | Mapped by CNV; Mapped by significant region | IEA |
| TLR4 | toll-like receptor 4 | Mapped by significant region | IC[16514062]; IDA[12594207] |
| CTSG | cathepsin G | Mapped by significant region | IEA |
| ADAM17 | ADAM metallopeptidase domain 17 | Mapped by significant region | IDA[18383040] |
| SCGB1A1 | secretoglobin, family 1A, member 1 (uteroglobin) | Mapped by significant region | IEA |
| EDNRA | endothelin receptor type A | Mapped by PBA pathway | IEA |
| TNFRSF11A | tumor necrosis factor receptor superfamily, member 11a, NFKB activator | Mapped by CNV | ISS[19940926] |
| NRF1 | nuclear respiratory factor 1 | Mapped by LD-proxy | IEA |