ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PYCRL
Symbol Alias	FLJ13852
Approved Name	pyrroline-5-carboxylate reductase-like
Location	8q24.3
Position	chr8:144686083-144691943, -
External Links	HGNC: 25846 Entrez Gene: 65263 Ensembl: ENSG00000104524 UCSC: uc003yyy.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy

Gene related studies (count: 0)

Gene related SNPs (count: 2)

rs_ID	Location	Functional Annotation
rs2278898	Chr8:144691512(Fwd)	NMD_transcript_variant; downstream_gene_variant; intron_variant; nc_transcript_variant; upstream_gene_variant
rs4874169	Chr8:144689686(Fwd)	NMD_transcript_variant; intron_variant; nc_transcript_variant

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 0)

Gene related GO terms (count: 4)

ID	Name	Type	No. of Genes in ADHDgene
GO:0055129	L-proline biosynthetic process	Biological Process	1
GO:0042802	identical protein binding	Molecular Function	70
GO:0004735	pyrroline-5-carboxylate reductase activity	Molecular Function	1
GO:0000166	nucleotide binding	Molecular Function	73

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00330	Arginine and proline metabolism	13

Genes shared at least 5 GO terms with PYCRL (count: 0)

Genes shared at least 2 KEGG pathways with PYCRL (count: 11)

Gene Symbol	Pathway Count	Pathway List
ALDH3A2	2	Metabolic pathways; Arginine and proline metabolism;
ARG1	2	Metabolic pathways; Arginine and proline metabolism;
CKMT1A	2	Metabolic pathways; Arginine and proline metabolism;
CKMT1B	2	Metabolic pathways; Arginine and proline metabolism;
GLUL	2	Metabolic pathways; Arginine and proline metabolism;
MAOA	2	Metabolic pathways; Arginine and proline metabolism;
MAOB	2	Metabolic pathways; Arginine and proline metabolism;
NOS1	2	Metabolic pathways; Arginine and proline metabolism;
ODC1	2	Metabolic pathways; Arginine and proline metabolism;
P4HA3	2	Metabolic pathways; Arginine and proline metabolism;
PRODH	2	Metabolic pathways; Arginine and proline metabolism;

View in gBrowse

Region: chr8:144686083..144691943 View in gBrowse