ADHDgene Database

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Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

SNP Report

Basic Info

Name	rs1040399 dbSNP Ensembl
Location	chrX:43625399(Fwd)
Variant Alleles	G/A
Ancestral Allele	G
Functional Annotation	downstream_gene_variant.
Consequence to Transcript	downstream_gene_variant(ENST00000378069; ENST00000536181; ENST00000538942)
No. of Studies	1 (significant: 1; non-significant: 0; trend: 0)
Source	Literature-origin

SNP related studies (count: 1)

Reference	Allele Change	Risk Allele	Statistical Values	Author Comments	Result of Statistical Analysis
Li J, 2008	C/T		TDT P-value=1.87E-6, X²=22.72 TDT P-value=1.87E-6, X²=22.72	significantly biased transmitted to ADHD offspring significantly biased transmitted to ADHD offspring	Significant

SNP related genes (count: 1)

Literature-origin genes (count: 1)

Approved Symbol	Approved Name	Location	No. of Studies (significant/non-significant/trend)
MAOB	monoamine oxidase B	Xp11.4-p11.3	6(2/4/0)

Genes from other sources (count: 0)

SNPs in LD with rs1040399 (count: 34) View in gBrowse (chrX:43614634..43684216 )

The LD data used here is based on HapMap rel#27. LD SNP pairs were selected with a threshold r²>=0.8.

Literature-origin SNPs (count: 0)

LD-proxies (count: 34)

rs_ID	Functional Annotation	r²[population]
rs5952671	intron_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs2092042	intron_variant	0.948[GIH]; 1.0[YRI]
rs2283727	intron_variant	0.948[GIH]
rs12558036	downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs12394221	intron_variant; nc_transcript_variant	0.948[GIH]
rs3027428		1.0[ASW]; 1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 1.0[LWK]; 1.0[MEX]; 1.0[YRI]
rs7888450	intron_variant	0.948[GIH]
rs7892217	intron_variant	0.948[GIH]; 1.0[YRI]
rs7890899		0.892[CHB]; 0.896[CHD]; 1.0[JPT]; 1.0[MEX]
rs7890174	intron_variant	0.948[GIH]
rs3027453	intron_variant; nc_transcript_variant	0.948[GIH]
rs2239449	intron_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs1014876	intron_variant; nc_transcript_variant	0.948[GIH]; 1.0[YRI]
rs3027461	intron_variant; nc_transcript_variant	0.948[GIH]; 1.0[YRI]
rs2239450	intron_variant; nc_transcript_variant	0.948[GIH]; 1.0[YRI]
rs2092041	intron_variant	0.948[GIH]; 1.0[YRI]
rs3027416		0.892[CHB]; 1.0[JPT]
rs3027439	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs3027426		1.0[CHB]; 1.0[JPT]
rs3027458	intron_variant; nc_transcript_variant	0.948[GIH]
rs17310637	intron_variant	0.948[GIH]; 1.0[YRI]
rs1040398	downstream_gene_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs3027421		0.892[CHB]; 1.0[JPT]
rs3027438	3_prime_UTR_variant; downstream_gene_variant	1.0[ASW]; 1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[YRI]
rs7886240	downstream_gene_variant	1.0[CHB]; 0.896[CHD]; 1.0[JPT]; 1.0[MEX]
rs3027440	3_prime_UTR_variant; downstream_gene_variant	1.0[ASW]; 1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[YRI]
rs3027431	downstream_gene_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs7884135	downstream_gene_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 1.0[MEX]
rs7067187	intron_variant; nc_transcript_variant	1.0[YRI]
rs2072745	3_prime_UTR_variant; downstream_gene_variant	1.0[CHB]; 1.0[JPT]
rs3027425		1.0[CHB]; 1.0[JPT]
rs3027435	downstream_gene_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]
rs6324	3_prime_UTR_variant; synonymous_variant	1.0[ASW]; 1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[LWK]; 1.0[MEX]; 1.0[YRI]
rs3027441	intron_variant; splice_region_variant	1.0[CHB]; 0.948[CHD]; 1.0[JPT]; 0.948[GIH]; 1.0[MEX]