ADHDgene Database

Gene Report

Basic Info

Approved Symbol	CARNS1
Previous Symbol	ATPGD1
Symbol Alias	KIAA1394
Approved Name	carnosine synthase 1
Previous Name	ATP-grasp domain containing 1
Location	11q13.1
Position	chr11:67182439-67193078, +
External Links	HGNC: 29268 Entrez Gene: 57571 Ensembl: ENSG00000172508 UCSC: uc009yrp.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 7)

ID	Name	Type	No. of Genes in ADHDgene
GO:0005524	ATP binding	Molecular Function	228
GO:0047730	carnosine synthase activity	Molecular Function	1
GO:0046872	metal ion binding	Molecular Function	170
GO:0006200	ATP catabolic process	Biological Process	6
GO:0005575	cellular_component	Cellular Component	98
GO:0035499	carnosine biosynthetic process	Biological Process	1
GO:0016887	ATPase activity	Molecular Function	14

Gene related KEGG pathways (count: 3)

ID	Name	No. of Genes in ADHDgene
hsa00330	Arginine and proline metabolism	13
hsa00410	beta-Alanine metabolism	8
hsa00340	Histidine metabolism	12

Genes shared at least 5 GO terms with CARNS1 (count: 0)

Genes shared at least 2 KEGG pathways with CARNS1 (count: 6)

Gene Symbol	Pathway Count	Pathway List
ALDH3A2	3	Arginine and proline metabolism; beta-Alanine metabolism; Histidine metabolism;
MAOA	2	Arginine and proline metabolism; Histidine metabolism;
MAOB	2	Arginine and proline metabolism; Histidine metabolism;
ALDH3A1	2	beta-Alanine metabolism; Histidine metabolism;
ALDH3B1	2	beta-Alanine metabolism; Histidine metabolism;
ALDH3B2	2	beta-Alanine metabolism; Histidine metabolism;

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Region: chr11:67182439..67193078 View in gBrowse