ADHDgene Database

Gene Report

Basic Info

Approved Symbol	ALAD
Symbol Alias	ALADH, PBGS
Approved Name	aminolevulinate dehydratase
Previous Name	aminolevulinate, delta-, dehydratase
Name Alias	porphobilinogen synthase
Location	9q32
Position	chr9:116148592-116163618, -
External Links	HGNC: 395 Entrez Gene: 210 Ensembl: ENSG00000148218 UCSC: uc011lxf.1
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0032791	lead ion binding	Molecular Function	IDA[11032836]	1
GO:0042802	identical protein binding	Molecular Function	IPI[11032836]	70
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0051260	protein homooligomerization	Biological Process	IPI[11032836]	34
GO:0006782	protoporphyrinogen IX biosynthetic process	Biological Process		3
GO:0006778	porphyrin-containing compound metabolic process	Biological Process		4
GO:0008270	zinc ion binding	Molecular Function	IDA[11032836]	323
GO:0006783	heme biosynthetic process	Biological Process	IDA[11032836]	3
GO:0003824	catalytic activity	Molecular Function	TAS[2063868]	15
GO:0005829	cytosol	Cellular Component		447
GO:0004655	porphobilinogen synthase activity	Molecular Function	IDA[11032836]	1

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00860	Porphyrin and chlorophyll metabolism	24

Genes shared at least 5 GO terms with ALAD (count: 1)

Gene Symbol	Pathway Count	Pathway List
HMBS	5	small molecule metabolic process; protoporphyrinogen IX biosynthetic process; porphyrin-containing compound metabolic process; heme biosynthetic process; cytosol;

Genes shared at least 2 KEGG pathways with ALAD (count: 22)

Gene Symbol	Pathway Count	Pathway List
EARS2	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
FECH	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
HMBS	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A1	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A10	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A3	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A4	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A5	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A6	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A7	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A8	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT1A9	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2A1	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2A2	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2A3	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B10	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B11	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B15	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B17	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B28	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B4	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;
UGT2B7	2	Metabolic pathways; Porphyrin and chlorophyll metabolism;

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Region: chr9:116148592..116163618 View in gBrowse