ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0016020
Name membrane
Type cellular component
No. of Genes in ADHDgene  155
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 155)

Literature-origin genes (count: 24)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
SLC18A2 solute carrier family 18 (vesicular monoamine transporter), member 2 10q25 2(0/2/0) TAS[8095030]
HTR4 5-hydroxytryptamine (serotonin) receptor 4, G protein-coupled 5q31-q33 1(1/0/0) IDA[16102731]
SORCS3 sortilin-related VPS10 domain containing receptor 3 10q23-q25 1(0/0/1) NAS[11499680]
HLA-DRB1 major histocompatibility complex, class II, DR beta 1 6p21.3 2(1/1/0) NAS
NUCB1 nucleobindin 1 19q13.33 1(0/0/1) IEA
ADRBK1 adrenergic, beta, receptor kinase 1 11q13 1(0/1/0) ISS
CDH23 cadherin-related 23 10q22.1 1(0/1/0) NAS[11138009]
SLC1A3 solute carrier family 1 (glial high affinity glutamate transporter), member 3 5p13 2(1/1/0) TAS[7521911]
DRD4 dopamine receptor D4 11p15.5 67(49/18/0) IDA[7512953]
CPLX4 complexin 4 18q21.32 1(1/0/0) IEA
VEGFA vascular endothelial growth factor A 6p12 1(0/1/0) IEA
SNAP25 synaptosomal-associated protein, 25kDa 20p12-p11.2 21(16/5/0) ISS
FADS2 fatty acid desaturase 2 11q12.2 3(3/0/0) TAS[9867867]
DBH dopamine beta-hydroxylase (dopamine beta-monooxygenase) 9q34 21(12/9/0) TAS[3443096]
CHRNA4 cholinergic receptor, nicotinic, alpha 4 (neuronal) 20q13.33 7(4/3/0) ISS
SLC7A10 solute carrier family 7 (neutral amino acid transporter light chain, asc system), member 10 19q13.11 1(1/0/0) TAS[10734121]
BCHE butyrylcholinesterase 3q26.1-q26.2 1(1/0/0) IEA
TIAM2 T-cell lymphoma invasion and metastasis 2 6q25 1(0/0/1) IEA
SH2B1 SH2B adaptor protein 1 16p11.2 1(0/1/0) IEA
FADS1 fatty acid desaturase 1 11q12-q13.1 3(1/2/0) NAS[10601301]
SLC6A1 solute carrier family 6 (neurotransmitter transporter), member 1 3p25.3 1(0/1/0) TAS[2387399]
SLC6A2 solute carrier family 6 (neurotransmitter transporter), member 2 16q12.2 16(10/5/1) TAS[2008212]
STS steroid sulfatase (microsomal), isozyme S Xp22.32 3(2/1/0) TAS[2668275]
SORCS1 sortilin-related VPS10 domain containing receptor 1 10q23-q25 1(0/0/1) IDA[12482870]

Genes from other sources Help (count: 131)

Approved Symbol Approved Name Source Evidence[PMID]
CDHR5 cadherin-related family member 5 Mapped by LD-proxy NAS
STK16 serine/threonine kinase 16 Mapped by significant region IEA
MARK2 MAP/microtubule affinity-regulating kinase 2 Mapped by significant region IMP[14976552]
SYT17 synaptotagmin XVII Mapped by significant region IEA
ARHGAP5 Rho GTPase activating protein 5 Mapped by significant region IEA
SIPA1 signal-induced proliferation-associated 1 Mapped by significant region IEA
PPP1R14C protein phosphatase 1, regulatory (inhibitor) subunit 14C Mapped by CNV IEA
FADS3 fatty acid desaturase 3 Mapped by LD-proxy; Mapped by significant region NAS[10860662]
INPP5A inositol polyphosphate-5-phosphatase, 40kDa Mapped by CNV NAS[8006039]
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 Mapped by CNV; Mapped by significant region TAS[1360704]
STK11 serine/threonine kinase 11 Mapped by CNV ISS
BFAR bifunctional apoptosis regulator Mapped by significant region IDA[10716992]
STMN1 stathmin 1 Mapped by PBA pathway IEA
ATP6V1F ATPase, H+ transporting, lysosomal 14kDa, V1 subunit F Mapped by LD-proxy IDA[18752060]
ARHGDIG Rho GDP dissociation inhibitor (GDI) gamma Mapped by significant region IEA
FUT4 fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific) Mapped by significant region TAS[1716630]
REEP1 receptor accessory protein 1 Mapped by CNV IDA
GNRHR gonadotropin-releasing hormone receptor Mapped by significant region TAS[9259321]
SYTL2 synaptotagmin-like 2 Mapped by significant region ISS
RHBDL1 rhomboid, veinlet-like 1 (Drosophila) Mapped by significant region TAS[9662444]
BSPRY B-box and SPRY domain containing Mapped by significant region IEA
ALG2 ALG2, alpha-1,3/1,6-mannosyltransferase Mapped by significant region IDA[16996505]
TSC2 tuberous sclerosis 2 Mapped by significant region IDA[16636147]
UGT2B17 UDP glucuronosyltransferase 2 family, polypeptide B17 Mapped by significant region TAS[8798464]
ARHGEF12 Rho guanine nucleotide exchange factor (GEF) 12 Mapped by significant region IEA
PNKD paroxysmal nonkinesigenic dyskinesia Mapped by significant region IEA
PCSK6 proprotein convertase subtilisin/kexin type 6 Mapped by CNV IEA
ROS1 c-ros oncogene 1 , receptor tyrosine kinase Mapped by significant region TAS[3785223]
SPA17 sperm autoantigenic protein 17 Mapped by significant region IEA
ARF6 ADP-ribosylation factor 6 Mapped by PBA pathway TAS[8702973]
FKBP2 FK506 binding protein 2, 13kDa Mapped by significant region IBA
NDUFAF2 NADH dehydrogenase (ubiquinone) complex I, assembly factor 2 Mapped by CNV IEA
ADCY4 adenylate cyclase 4 Mapped by significant region ISS
CDC42EP5 CDC42 effector protein (Rho GTPase binding) 5 Mapped by PBA pathway IDA[11035016]
RTN4R reticulon 4 receptor Mapped by CNV NAS
DSC1 desmocollin 1 Mapped by significant region TAS[7679953]
PLCB3 phospholipase C, beta 3 (phosphatidylinositol-specific) Mapped by significant region IEA
CPD carboxypeptidase D Mapped by CNV TAS[9064476]
RASL11B RAS-like, family 11, member B Mapped by CNV IEA
SORD sorbitol dehydrogenase Mapped by CNV IDA[8487505]
GRIN3A glutamate receptor, ionotropic, N-methyl-D-aspartate 3A Mapped by significant region IDA[17997397]
ITGB1BP1 integrin beta 1 binding protein 1 Mapped by significant region NAS[9281591]
BEST1 bestrophin 1 Mapped by significant region TAS[10737974]
CCND1 cyclin D1 Mapped by significant region IEA
BIRC6 baculoviral IAP repeat containing 6 Mapped by CNV IEA
CDC42EP2 CDC42 effector protein (Rho GTPase binding) 2 Mapped by significant region; Mapped by PBA pathway IDA[11035016]
PKMYT1 protein kinase, membrane associated tyrosine/threonine 1 Mapped by significant region TAS[9001210]
TSC1 tuberous sclerosis 1 Mapped by PBA pathway IDA[16636147]
FIBP fibroblast growth factor (acidic) intracellular binding protein Mapped by significant region IDA[9806903]
PLA2G4C phospholipase A2, group IVC (cytosolic, calcium-independent) Mapped by PBA pathway TAS[10085124]
RAB30 RAB30, member RAS oncogene family Mapped by significant region IEA
SLC14A2 solute carrier family 14 (urea transporter), member 2 Mapped by significant region TAS[8647271]
PNPLA8 patatin-like phospholipase domain containing 8 Mapped by PBA pathway IDA[10833412]
CNTNAP2 contactin associated protein-like 2 Mapped by CNV IDA[10624965]
AGAP3 ArfGAP with GTPase domain, ankyrin repeat and PH domain 3 Mapped by LD-proxy IEA
DPAGT1 dolichyl-phosphate (UDP-N-acetylglucosamine) N-acetylglucosaminephosphotransferase 1 (GlcNAc-1-P transferase) Mapped by significant region IDA[8179616]
ATXN2L ataxin 2-like Mapped by LD-proxy IDA[11784712]
PAPPA pregnancy-associated plasma protein A, pappalysin 1 Mapped by significant region IEA
ABCA3 ATP-binding cassette, sub-family A (ABC1), member 3 Mapped by significant region TAS[9027511]
PIK3C2G phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 gamma Mapped by LD-proxy IEA
FOLR1 folate receptor 1 (adult) Mapped by significant region TAS[2768245]
VEGFB vascular endothelial growth factor B Mapped by significant region IEA
CRBN cereblon Mapped by CNV IEA
PVRL1 poliovirus receptor-related 1 (herpesvirus entry mediator C) Mapped by significant region TAS[9616127]
ENPP7 ectonucleotide pyrophosphatase/phosphodiesterase 7 Mapped by PBA pathway NAS[12885774]
CHST10 carbohydrate sulfotransferase 10 Mapped by CNV TAS[9478973]
PDE4D phosphodiesterase 4D, cAMP-specific Mapped by CNV IEA
IGLL1 immunoglobulin lambda-like polypeptide 1 Mapped by CNV NAS[2501791]
DNAJC4 DnaJ (Hsp40) homolog, subfamily C, member 4 Mapped by significant region NAS[9473517]
PLD1 phospholipase D1, phosphatidylcholine-specific Mapped by PBA pathway TAS[8530346]
CACNB3 calcium channel, voltage-dependent, beta 3 subunit Mapped by PBA pathway IDA[16525042]
CUTA cutA divalent cation tolerance homolog (E. coli) Mapped by LD-proxy IDA[10800960]
EDNRA endothelin receptor type A Mapped by PBA pathway NAS
PLN phospholamban Mapped by significant region IDA[19708671]
FOLR3 folate receptor 3 (gamma) Mapped by significant region TAS[8110752]
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) Mapped by PBA pathway IEA
CXCR2 chemokine (C-X-C motif) receptor 2 Mapped by significant region IDA[10725748]
UGCG UDP-glucose ceramide glucosyltransferase Mapped by significant region TAS[8643456]
STX4 syntaxin 4 Mapped by CNV TAS[7690687]
GGT1 gamma-glutamyltransferase 1 Mapped by CNV NAS
PITPNM1 phosphatidylinositol transfer protein, membrane-associated 1 Mapped by significant region TAS[9245688]
SLC4A3 solute carrier family 4 (anion exchanger), member 3 Mapped by significant region TAS[7923606]
PI4K2B phosphatidylinositol 4-kinase type 2 beta Mapped by CNV IEA
SNX15 sorting nexin 15 Mapped by significant region NAS[11085978]
ACHE acetylcholinesterase (Yt blood group) Mapped by PBA pathway IDA[16262697]
VSIG2 V-set and immunoglobulin domain containing 2 Mapped by significant region TAS[9862345]
CUBN cubilin (intrinsic factor-cobalamin receptor) Mapped by CNV TAS[9478979]
PNPLA3 patatin-like phospholipase domain containing 3 Mapped by PBA pathway ISS
CXCR1 chemokine (C-X-C motif) receptor 1 Mapped by significant region TAS[10725748]
B3GNT6 UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 6 (core 3 synthase) Mapped by significant region NAS[11821425]
TELO2 telomere maintenance 2 Mapped by significant region IEA
SEMA3E sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E Mapped by CNV IEA
MAN1A1 mannosidase, alpha, class 1A, member 1 Mapped by significant region TAS[8223597]
UGT2B7 UDP glucuronosyltransferase 2 family, polypeptide B7 Mapped by significant region TAS[2159463]
PRSS21 protease, serine, 21 (testisin) Mapped by significant region TAS[9826525]
AVEN apoptosis, caspase activation inhibitor Mapped by CNV IDA[10949025]
MSLN mesothelin Mapped by significant region NAS[8552591]
ADORA2A adenosine A2a receptor Mapped by CNV TAS[10051547]
STARD10 StAR-related lipid transfer (START) domain containing 10 Mapped by significant region IEA
EIF2B1 eukaryotic translation initiation factor 2B, subunit 1 alpha, 26kDa Mapped by CNV IDA[9235896]
INVS inversin Mapped by significant region IEA
PLCD4 phospholipase C, delta 4 Mapped by significant region IEA
ATP2A1 ATPase, Ca++ transporting, cardiac muscle, fast twitch 1 Mapped by Literature SNP ISS
MMP25 matrix metallopeptidase 25 Mapped by significant region NAS[11034316]
DSC3 desmocollin 3 Mapped by significant region TAS[7929347]
SVEP1 sushi, von Willebrand factor type A, EGF and pentraxin domain containing 1 Mapped by significant region IEA
EFEMP2 EGF containing fibulin-like extracellular matrix protein 2 Mapped by significant region IEA
RC3H2 ring finger and CCCH-type domains 2 Mapped by significant region IDA[10938276]
IL12B interleukin 12B (natural killer cell stimulatory factor 2, cytotoxic lymphocyte maturation factor 2, p40) Mapped by significant region IEA
DCHS1 dachsous cadherin-related 1 Mapped by CNV NAS[9199196]
CLINT1 clathrin interactor 1 Mapped by significant region IEA
RYR2 ryanodine receptor 2 (cardiac) Mapped by CNV; Mapped by PBA pathway IDA[12443530]
CHRM1 cholinergic receptor, muscarinic 1 Mapped by significant region; Mapped by PBA pathway TAS[7925360]
ADCY2 adenylate cyclase 2 (brain) Mapped by significant region ISS
GOPC golgi-associated PDZ and coiled-coil motif containing Mapped by significant region IDA[11707463]
NPVF neuropeptide VF precursor Mapped by CNV; Mapped by significant region NAS
NAPG N-ethylmaleimide-sensitive factor attachment protein, gamma Mapped by PBA pathway IEA
TMOD1 tropomodulin 1 Mapped by significant region IEA
SLC4A2 solute carrier family 4 (anion exchanger), member 2 Mapped by Literature SNP TAS[3015590]
MPP6 membrane protein, palmitoylated 6 (MAGUK p55 subfamily member 6) Mapped by CNV; Mapped by significant region NAS[11311936]
TM6SF2 transmembrane 6 superfamily member 2 Mapped by LD-proxy NAS
GAPVD1 GTPase activating protein and VPS9 domains 1 Mapped by significant region IEA
CCND3 cyclin D3 Mapped by CNV IEA
P2RX3 purinergic receptor P2X, ligand-gated ion channel, 3 Mapped by significant region IBA
PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma Mapped by CNV IDA[12507995]
RAB1B RAB1B, member RAS oncogene family Mapped by significant region IEA
RAB6A RAB6A, member RAS oncogene family Mapped by CNV; Mapped by significant region IDA[12447383]
NRBP1 nuclear receptor binding protein 1 Mapped by PBA pathway IEA
CCDC88A coiled-coil domain containing 88A Mapped by PBA pathway IDA[15749703]
FOLR2 folate receptor 2 (fetal) Mapped by significant region TAS[2605182]
CHN2 chimerin 2 Mapped by CNV IEA