ADHDgene Database

Gene Report

Basic Info

Approved Symbol	PAPPA
Symbol Alias	PAPP-A, PAPPA1, IGFBP-4ase, PAPA, ASBABP2, DIPLA1
Approved Name	pregnancy-associated plasma protein A, pappalysin 1
Name Alias	insulin-like growth factor-dependent IGF binding protein-4 protease, "aspecific BCL2 ARE-binding protein 2", "differentially placenta 1 expressed protein"
Location	9q33.1
Position	chr9:118916071-119164601, +
External Links	HGNC: 8602 Entrez Gene: 5069 Ensembl: ENSG00000182752 UCSC: uc004bjn.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 2)

Region Name	Position	No. of Studies (significant/non-significant/trend)
9q33	chr9:117700000-130300000	2 (1/1/0)
9q31.1-33.1	chr9:102600000-122500000	1 (1/0/0)

Gene related GO terms (count: 11)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0016020	membrane	Cellular Component		139
GO:0008270	zinc ion binding	Molecular Function	NAS[10077652]	323
GO:0008237	metallopeptidase activity	Molecular Function	IDA[10077652]; NAS[10913121]	13
GO:0007565	female pregnancy	Biological Process	NAS[10077652]	14
GO:0051384	response to glucocorticoid stimulus	Biological Process		17
GO:0032354	response to follicle-stimulating hormone stimulus	Biological Process		1
GO:0030154	cell differentiation	Biological Process		51
GO:0004175	endopeptidase activity	Molecular Function		4
GO:0005576	extracellular region	Cellular Component	IDA[10077652]; NAS[10913121]	240
GO:0005615	extracellular space	Cellular Component		126
GO:0006508	proteolysis	Biological Process		102

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with PAPPA (count: 0)

Genes shared at least 2 KEGG pathways with PAPPA (count: 0)

View in gBrowse

Region: chr9:118916071..119164601 View in gBrowse