ADHDgene Database

Gene Report

Basic Info

Approved Symbol	FADS3
Previous Symbol	LLCDL3
Symbol Alias	CYB5RP
Approved Name	fatty acid desaturase 3
Name Alias	"delta-9-desaturase"
Location	11q12-q13.1
Position	chr11:61640991-61659523, -1
External Links	HGNC: 3576 Entrez Gene: 3995 Ensembl: ENSG00000221968 UCSC: uc001nsm.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by LD-proxy; Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 3)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 9)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0005506	iron ion binding	molecular function	IEA	26
GO:0016717	oxidoreductase activity, acting on paired donors, with oxidation of a pair of donors resulting in the reduction of molecular oxygen to two molecules of water	molecular function	IEA	1
GO:0005789	endoplasmic reticulum membrane	cellular component	IEA	159
GO:0016020	membrane	cellular component	NAS[10860662]	155
GO:0016021	integral to membrane	cellular component	IEA	932
GO:0022900	electron transport chain	biological process	IEA	12
GO:0020037	heme binding	molecular function	IEA	28
GO:0003674	molecular_function	molecular function	ND	149
GO:0006636	unsaturated fatty acid biosynthetic process	biological process	NAS[10860662]	4

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with FADS3 (count: 3)

Gene Symbol	Pathway Count	Pathway List
FADS1	7	iron ion binding; endoplasmic reticulum membrane; membrane; integral to membrane; electron transport chain; heme binding; unsaturated fatty acid biosynthetic process;
FADS2	6	iron ion binding; endoplasmic reticulum membrane; membrane; electron transport chain; heme binding; unsaturated fatty acid biosynthetic process;
FA2H	5	iron ion binding; endoplasmic reticulum membrane; integral to membrane; electron transport chain; heme binding;

Genes shared at least 2 KEGG pathways with FADS3 (count: 0)

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Region: chr11:61640991..61659523 View in gBrowse