ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

GO Report

Basic Info
ID GO:0005506
Name iron ion binding
Type molecular function
No. of Genes in ADHDgene  26
Source Pathway by Database Search

PBA Result (with statistical significance of FDR<0.05)

GO related genes in ADHDgene (count: 26)

Literature-origin genes (count: 6)

Approved Symbol Approved Name Location No. of Studies (significant/non-significant/trend) Evidence[PMID]
FADS1 fatty acid desaturase 1 11q12-q13.1 3(1/2/0) IEA
NOS1 nitric oxide synthase 1 (neuronal) 12q24.22 1(1/0/0) IEA
TPH1 tryptophan hydroxylase 1 11p15.3-p14 6(2/4/0) IEA
TPH2 tryptophan hydroxylase 2 12q15 11(8/3/0) IEA
TDO2 tryptophan 2,3-dioxygenase 4q31-q32 1(1/0/0) IEA
FADS2 fatty acid desaturase 2 11q12.2 3(3/0/0) IEA

Genes from other sources Help (count: 20)

Approved Symbol Approved Name Source Evidence[PMID]
HBG2 hemoglobin, gamma G Mapped by CNV IEA
HBQ1 hemoglobin, theta 1 Mapped by significant region IEA
SC5D sterol-C5-desaturase Mapped by significant region IEA
P4HA3 prolyl 4-hydroxylase, alpha polypeptide III Mapped by significant region IEA
CYP27A1 cytochrome P450, family 27, subfamily A, polypeptide 1 Mapped by significant region IEA
FDX1 ferredoxin 1 Mapped by significant region TAS[2969697]
PHF2 PHD finger protein 2 Mapped by significant region IDA
CYP2E1 cytochrome P450, family 2, subfamily E, polypeptide 1 Mapped by CNV IEA
EGLN3 egl-9 family hypoxia-inducible factor 3 Mapped by Literature SNP IEA
PPEF2 protein phosphatase, EF-hand calcium binding domain 2 Mapped by CNV IEA
HBM hemoglobin, mu Mapped by significant region IEA
FTH1 ferritin, heavy polypeptide 1 Mapped by significant region TAS[3020541]
CYCS cytochrome c, somatic Mapped by CNV; Mapped by significant region IEA
FADS3 fatty acid desaturase 3 Mapped by LD-proxy; Mapped by significant region IEA
HBZ hemoglobin, zeta Mapped by significant region IEA
FA2H fatty acid 2-hydroxylase Mapped by significant region IEA
SDHD succinate dehydrogenase complex, subunit D, integral membrane protein Mapped by significant region IEA
CYP17A1 cytochrome P450, family 17, subfamily A, polypeptide 1 Mapped by LD-proxy IEA
MTRR 5-methyltetrahydrofolate-homocysteine methyltransferase reductase Mapped by significant region IEA
HBA2 hemoglobin, alpha 2 Mapped by significant region IEA