ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol FADS2
Previous Symbol LLCDL2
Symbol Alias FADSD6, D6D, TU13, DES6, SLL0262
Approved Name fatty acid desaturase 2
Name Alias delta-6-desaturase
Location 11q12.2
Position chr11:61583728-61634826, +
External Links HGNC: 3575
Entrez Gene: 9415
Ensembl: ENSG00000134824
UCSC: uc001nsl.1
No. of Studies 3 (significant: 3; non-significant: 0; trend: 0)
Source Literature-origin; Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Brookes K, 2006 UNPHASED TDT P-value=0.039, global P-value=0.389, WHAP TDT P_sum P-value=0.798; OR=1.2, one or more SNPs with nominal P-value<0.05 located in this gene Significant
Brookes KJ, 2006(a) 1 SNP showed significant association in both case-control and within-family analyses, which are suggestive of an association between FADS2 and ADHD Significant
Mick E, 2010 Gene-based set test P-value=0.047. Significant gene-based set tests of association with selected candidates, but contains no significant or Trend associated SNPs. Significant

Gene related SNPs (count: 34)

Literature-origin SNPs (count: 4)

LD-proxies (count: 30)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Gene related GO terms (count: 12)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 12)

Gene related KEGG pathways (count: 3)

Genes shared at least 5 GO terms with FADS2 (count: 2)

Genes shared at least 2 KEGG pathways with FADS2 (count: 0)

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Region: chr11:61583728..61634826 View in gBrowse
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