ADHDgene Database
  • Published Variant
  • Published Gene: 359
  • Published Region: 128
  • Pathway by PBA: 8
  • Study: 361

Gene Report

Basic Info
Approved Symbol FADS1
Previous Symbol LLCDL1
Symbol Alias D5D, FADSD5, TU12, FADS6
Approved Name fatty acid desaturase 1
Name Alias delta-5 desaturase
Location 11q12-q13.1
Position chr11:61567097-61596790, -
External Links HGNC: 3574
Entrez Gene: 3992
Ensembl: ENSG00000149485
UCSC: uc010rlm.1
No. of Studies 3 (significant: 1; non-significant: 2; trend: 0)
Source Literature-origin; Mapped by LD-proxy; Mapped by literature SNP; Mapped by significant region

Gene related studies (count: 3)
Reference Statistical Values/Author Comments Result of Statistical Analysis
Brookes KJ, 2006(a) no evidence from case-control or within family tests of association for a haplotype specific association with the two SNPs in FADS1 Non-significant
Mick E, 2010 Gene-based set test P-value=0.019. Significant gene-based set tests of association with selected candidates, but contains no significant or Trend associated SNPs. Significant
Brookes K, 2006 UNPHASED TDT P-value=0.108, global P-value=0.309, WHAP TDT P_sum P-value=0.684, no SNP with nominal P-value<0.05 located in this gene Non-significant

Gene related SNPs (count: 15)

Literature-origin SNPs (count: 2)

LD-proxies (count: 13)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Gene related GO terms (count: 28)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 28)

Gene related KEGG pathways (count: 1)

Genes shared at least 5 GO terms with FADS1 (count: 11)

Genes shared at least 2 KEGG pathways with FADS1 (count: 0)

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Region: chr11:61567097..61596790 View in gBrowse
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