ADHDgene Database

Gene Report

Basic Info

Approved Symbol	SC5DL
Approved Name	sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, S. cerevisiae)-like
Previous Name	sterol-C5-desaturase (fungal ERG3, delta-5-desaturase)-like, "sterol-C5-desaturase (ERG3 delta-5-desaturase homolog, fungal)-like"
Location	11q23.3
Position	chr11:121163162-121184119, +
External Links	HGNC: 10547 Entrez Gene: 6309 Ensembl: ENSG00000109929 UCSC: uc001pxu.2
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
11q	chr11:53700000-135006516	2 (1/1/0)

Gene related GO terms (count: 10)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0044281	small molecule metabolic process	Biological Process		248
GO:0050046	lathosterol oxidase activity	Molecular Function		1
GO:0006629	lipid metabolic process	Biological Process	TAS[8976377]	51
GO:0005789	endoplasmic reticulum membrane	Cellular Component		140
GO:0005506	iron ion binding	Molecular Function		20
GO:0000248	C-5 sterol desaturase activity	Molecular Function		2
GO:0033490	cholesterol biosynthetic process via lathosterol	Biological Process		1
GO:0016021	integral to membrane	Cellular Component		845
GO:0006695	cholesterol biosynthetic process	Biological Process		7
GO:0006633	fatty acid biosynthetic process	Biological Process		16

Gene related KEGG pathways (count: 2)

ID	Name	No. of Genes in ADHDgene	Brief Description
hsa01100	Metabolic pathways	237
hsa00100	Steroid biosynthesis	4

Genes shared at least 5 GO terms with SC5DL (count: 1)

Gene Symbol	Pathway Count	Pathway List
FADS1	5	small molecule metabolic process; endoplasmic reticulum membrane; iron ion binding; C-5 sterol desaturase activity; integral to membrane;

Genes shared at least 2 KEGG pathways with SC5DL (count: 3)

Gene Symbol	Pathway Count	Pathway List
DHCR7	2	Metabolic pathways; Steroid biosynthesis;
SQLE	2	Metabolic pathways; Steroid biosynthesis;
TM7SF2	2	Metabolic pathways; Steroid biosynthesis;

View in gBrowse

Region: chr11:121163162..121184119 View in gBrowse