ADHDgene Database

Hot Results

Quick Search

Keyword:
Type:

Large-scale studies

Data Summary

Published Variant
- SNP: 1391
- CNV: 398
- Others: 173
Published Gene: 359
Published Region: 128
Pathway by PBA: 8
Study: 361

Detail ...

Gene Report

Basic Info

Approved Symbol	DSC3
Previous Symbol	DSC4
Symbol Alias	CDHF3, DSC, DSC1, DSC2
Approved Name	desmocollin 3
Location	18q12.1
Position	chr18:28570052-28622781, -
External Links	HGNC: 3037 Entrez Gene: 1825 Ensembl: ENSG00000134762 UCSC: uc002kwj.3
No. of Studies	0 (significant: 0; non-significant: 0; trend: 0)
Source	Mapped by significant region

Gene related studies (count: 0)

Gene related SNPs (count: 0)

Gene related CNVs (count: 0)

Gene related other variant (count: 0)

Gene related regions (count: 1)

Region Name	Position	No. of Studies (significant/non-significant/trend)
18q11.2-12.3	chr18:19000000-43500000	1 (1/0/0)

Gene related GO terms (count: 13)

GO terms by PBA (with statistical significance of FDR<0.05) (count: 0)

GO terms by database search (count: 13)

ID	Name	Type	Evidence[PMID]	No. of Genes in ADHDgene
GO:0001701	in utero embryonic development	Biological Process		32
GO:0005576	extracellular region	Cellular Component		240
GO:0005509	calcium ion binding	Molecular Function		124
GO:0005886	plasma membrane	Cellular Component		772
GO:0005737	cytoplasm	Cellular Component		690
GO:0007156	homophilic cell adhesion	Biological Process		27
GO:0016020	membrane	Cellular Component	TAS[7929347]	139
GO:0005911	cell-cell junction	Cellular Component	TAS[7929347]	20
GO:0007155	cell adhesion	Biological Process	TAS[7929347]	86
GO:0045295	gamma-catenin binding	Molecular Function	IPI[7983064]	6
GO:0050821	protein stabilization	Biological Process	IDA[7983064]	10
GO:0016021	integral to membrane	Cellular Component		845
GO:0030057	desmosome	Cellular Component		9

Gene related KEGG pathways (count: 0)

Genes shared at least 5 GO terms with DSC3 (count: 15)

Gene Symbol	Pathway Count	Pathway List
DSG1	8	calcium ion binding; plasma membrane; homophilic cell adhesion; cell-cell junction; gamma-catenin binding; protein stabilization; integral to membrane; desmosome;
CDH2	7	calcium ion binding; plasma membrane; homophilic cell adhesion; cell-cell junction; cell adhesion; gamma-catenin binding; integral to membrane;
DSG2	7	calcium ion binding; plasma membrane; homophilic cell adhesion; cell-cell junction; cell adhesion; integral to membrane; desmosome;
PVRL1	6	extracellular region; plasma membrane; homophilic cell adhesion; membrane; cell adhesion; integral to membrane;
CDH6	6	calcium ion binding; plasma membrane; cytoplasm; homophilic cell adhesion; cell adhesion; integral to membrane;
CDHR5	6	calcium ion binding; plasma membrane; homophilic cell adhesion; membrane; cell adhesion; integral to membrane;
DSC1	6	calcium ion binding; plasma membrane; homophilic cell adhesion; membrane; integral to membrane; desmosome;
DSC2	6	calcium ion binding; plasma membrane; homophilic cell adhesion; cell adhesion; integral to membrane; desmosome;
SVEP1	5	extracellular region; calcium ion binding; cytoplasm; membrane; cell adhesion;
CDH15	5	calcium ion binding; plasma membrane; homophilic cell adhesion; cell adhesion; integral to membrane;
CDH23	5	calcium ion binding; plasma membrane; homophilic cell adhesion; membrane; integral to membrane;
CELSR2	5	calcium ion binding; plasma membrane; cytoplasm; homophilic cell adhesion; integral to membrane;
DCHS1	5	calcium ion binding; plasma membrane; homophilic cell adhesion; membrane; integral to membrane;
DSG3	5	calcium ion binding; plasma membrane; homophilic cell adhesion; integral to membrane; desmosome;
DSG4	5	calcium ion binding; plasma membrane; homophilic cell adhesion; integral to membrane; desmosome;

Genes shared at least 2 KEGG pathways with DSC3 (count: 0)

View in gBrowse

Region: chr18:28570052..28622781 View in gBrowse